May 06 2020 73 mins 63
Nels and Vincent continue their discussion of SARS-CoV-2 evolution, with a report that the coronavirus proofreading enzyme stimulates RNA recombination, and debunking the conclusion that a change in the viral spike glycoprotein is associated with increased human to human transmission.
Hosts: Nels Elde and Vincent Racaniello
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- CoV proofreading enzyme stimulates recombination (bioRxiv)
- CoV spike mutation pipeline (bioRxiv)
- Issues with CoV sequencing data (virological.org)
- Bill Hanage on selection vs bottleneck (threader.app)
- Image credit
- Time stamps by Jolene. Thanks!
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