Life Extension Advocacy Foundation

Jan 01 2021 23 mins 1

Let's Crowdfund the Cure for Aging: http://www.lifespan.io/ We promote the advancement of biomedical technologies which can increase human lifespan and raise awareness regarding societal benefits of life extension. Videos will be appearing in the next few months, but please subscribe — enough support will gain us access to an amazing film studio which will enable us to hit the ground running!





Rejuvenation Roundup December 2020
Jan 01 2021 19 mins  
This month on the Rejuvenation Roundup Podcast, Ryan O'Shea of Future Grind talks about a nanoparticle-based delivery system for CRISPR, the gene responsible for the effects of caloric restriction, partial cellular reprogramming to restore the vision of mice, a human study of glucosamine and chondroitin, a small molecule that restores memory by inhibiting the integrative stress response, Russian biohackers and plasma dilution, Ending Age-Related Diseases 2020 videos, and Longevity Therapeutics 2021. 0:00 Intro 1:00 Nanoparticles and CRISPR 3:00 Genetics, Caloric Restriction, and Longevity 3:55 Partial Cellular Reprogramming to Improve Vision 5:00 Glucosamine and Chondroitin Supplementation 5:57 A Small Molecule Restores Memory 7:35 Russian Biohackers Experiment With Plasma Dilution 8:45 Ending Age-Related Diseases 2020 Videos 18:04 Longevity Therapeutics 2021 HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO NEWS & SOCIAL MEDIA ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ News: https://www.lifespan.io/news Facebook: https://www.lifespan.io/facebook Instagram: https://www.lifespan.io/instagram LinkedIn: https://www.lifespan.io/linkedin Twitter: https://www.lifespan.io/twitter Discord: https://www.lifespan.io/discord Newsletter: https://www.lifespan.io/newsletter YOUTUBE COLLABORATIONS: ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Kurzgesagt: https://www.youtube.com/watch?v=MjdpR-TY6QU Life Noggin: https://www.youtube.com/watch?v=EEO4bHbxRgo TOOLS & RESOURCES ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Research Roadmap: https://www.lifespan.io/roadmap Investor Network: https://www.lifespan.io/investor Journal Club: https://www.lifespan.io/journalclub Conferences: https://www.lifespan.io/conference MORE INFO ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Age-related diseases, such as Alzheimer's, heart disease, and cancer, are some of the worst drains on our society, both in terms of personal suffering and socio-economic effects. One of the reasons why our work is so important is that, historically, research aimed at tackling these diseases has been focused at the end stages of such maladies, when it is too late to reverse the damage that has been done. A good analogy is a tree: what makes more sense — spending a ton of money trying to cure a branch of a branch, or directing that focus to the trunk of the tree itself? Aging is the greatest risk factor for all of these major diseases, and in many cases, it is ultimately the primary cause. While it may seem hard to believe, biological science has finally progressed enough to begin targeting the root mechanisms of aging, and — thanks to the efforts of the world-renowned researchers and labs we work with, such as Drs. David Sinclair, George Church, and Aubrey de Grey — is beginning to bring aging, and therefore these diseases, under medical control. Everything we've done thus far, and everything we will do in the future, is thanks to your support, and that is why we are asking you to stand with us - to be a Lifespan Hero and help us improve the lives of not just ourselves and our family members, but everyone in the entire world. Together, we can do this. Be a Hero. JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech


Alexandra Bause | Biotech VC Meets Impact Investing With the Mission to Enhance Human Health
Dec 25 2020 24 mins  
In this presentation given at Ending Age-Related Diseases 2020, Dr. Alexandra Bause of Apollo Venture discusses biotech investment in an aging world, explaining current demographic trends, the multimorbidities associated with an aging population, and the need of healthspan-enhancing biotechnology to meet this need. She brings up the hallmarks of aging and suggests multiple methods of treatment to ameliorate these diseases and maintain good health throughout life. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech



Isabelle Schiffer | Rejuvenation Therapies from Bench to Bedside
Dec 24 2020 22 mins  
In this presentation given at Ending Age-Related Diseases 2020, Dr. Isabelle Schiffer of the Forever Healthy Foundation discusses the state of rejuvenation therapies and progress in bringing them into clinical practice. She discusses the rejuvenation market along with senotherapies, which target senescent cells in order to treat age-related diseases. This presentation featured the dasatinib + quercetin senolytic combination along with the supplement fisetin. As she explains, the problems with senolytics as a clinical therapy, as things stand today, are that there are no treatment protocols and no clinical endpoints. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech




Ronjon Nag | AI and Aging at Ending Age-Related Diseases 2020
Dec 23 2020 29 mins  
In this presentation given at Ending Age-Related Diseases 2020, Dr. Ronjon Nag of the R42 Institute discusses his company's endeavors into biotechnology investment along with the nature of artificial intelligence and how it can be used to defeat aging. He discusses the myriad forms of artificial intelligence, including machine learning systems, and the achievements that they have accomplished in recent years. He further discusses the ways in which AI can use data sets to find ways for us to live longer. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech #AI #MachineLearning


Sajad Zalzala | Phase IV Rapamycin Longevity Trial: A Paradigm Shift in Longevity Clinical Trials
Dec 22 2020 22 mins  
In this presentation given at Ending Age-Related Diseases 2020, Dr. Sajad Zalzala of AgelessRx discusses PEARL, a human trial of rapamycin that uses the participation of ordinary people in order to get a large sample size without the expense of a traditional clinical trial. He discusses the use and effectiveness of rapamycin as an aging treatment in previous studies of both rodents and people. He discusses the objectives of PEARL and provides reasons why this groundbreaking trial will not only provide evidence for the effectiveness of rapamycin in human beings but provide a new framework for future trials, aiding human longevity as a whole. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech


Reversing Cellular Age in Mice Restores Vision | Lifespan News
Dec 22 2020 11 mins  
SAVE THE DATE! Lifespan News is moving to X10's new channel on January 5, 2021! https://www.youtube.com/lifextenshow ▼▼ Description, sources, and more below ▼▼ In this episode of Lifespan News: 0:00 Intro 1:25 Reversing Cellular Age in Mice Restores Vision 2:28 Drug Reverses Age-Related Cognitive Decline Within Days 4:34 A Key Gene Links Diet and Longevity 6:35 Kidney Progenitor Cells Derived from Urine 8:09 Epigenetics and memory loss in Alzheimer’s Visit https://youtube.com/BrentNally for more of Brent's content! Executive Producer: Keith Comito Producer: Nicola Bagalà Assistant Producer: Sedeer el-Showk Video Editors: Tim Maupin, Brent Nally Text Editor: Josh Conway SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Reversing Cellular Age in Mice Restores Vision: https://www.lifespan.io/news/reversing-cellular-age-in-mice-restores-vision/ https://medicalxpress.com/news/2020-12-scientists-reverse-age-related-vision-loss.html Drug Reverses Age-Related Cognitive Decline Within Days: https://neurosciencenews.com/age-cognition-reversal-drug-17347/ https://elifesciences.org/articles/62048 A Key Gene Links Diet and Longevity: https://www.lifespan.io/news/a-key-gene-links-diet-and-longevity/ https://www.eurekalert.org/pub_releases/2020-11/m-smf112420.php Kidney Progenitor Cells Derived from Urine: https://www.lifespan.io/news/kidney-progenitor-cells-derived-from-urine/ https://www.nature.com/articles/s41598-020-57723-2 Epigenetics and memory loss in Alzheimer’s: https://advances.sciencemag.org/content/6/50/eabc8096 https://www.buffalo.edu/news/releases/2020/12/007.html HOW YOU CAN SUPPORT US ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ If you’d like to help us run this show and/or help Lifespan.io end age-related diseases, you can become a Lifespan Hero: https://lifespan.io/hero. Your support means the world to us! FOLLOW US EVERYWHERE ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Website: https://lifespan.io/lifextenshow Instagram: https://www.instagram.com/lifextenshow/ Facebook: https://www.facebook.com/watch/lifespanio/659351311315977/ Facebook (Lifespan News): https://www.facebook.com/watch/lifespanio/316625179521524/ Twitter: https://twitter.com/lifespanio Discord: https://discord.gg/HwTX7gR FOOTAGE, IMAGES, AND MUSIC CREDITS ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Intro music: "Retro 80s technology" by Eric Matyas ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ #Aging #Brain #Vision #Epigenetics #Glaucoma #Diet #Kidney #Alzheimers



Paul Spiegel | Beyond Retirement: A New Social Compact for the Age of Longevity
Dec 21 2020 20 mins  
In this presentation given at Ending Age-Related Diseases 2020, Paul Spiegel of Eclectic Law discusses the future of retirement in a world without age-related diseases. He discusses the formation of a new social contract in which radical life extension is given freely in order to remove the problems and expenses posed by pensions and retirement funds and to allow citizens to live happier, consistently productive, and much longer lives. In such a world, there would be no such thing as permanent retirement - because there would be no such thing as old age. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech




Lifespan Docs | Patricia Wolff of Meds & Food for Kids Speaks Out About Longevity
Dec 18 2020 4 mins  
Here at Lifespan.io, we are passionate about engaging with people about the exciting potential of longer and healthier lives through science. Age-related diseases not only kill the people we care about, they cause tremendous suffering along the way, not only for the people struggling with these diseases but for the loved ones who watch them suffer. We believe in building a better world in which age-related diseases are a thing of the past and in which families and friends can enjoy longer, healthy lives together. As part of the drive to end age-related diseases, we are producing Lifespan Docs, a new series of short documentaries. These short films created by Tim Maupin will show how longer and healthy lives could change people’s lives for the better, and they will include how people from many walks of life feel about the subject. Dr. Patricia Wolff runs the charity Meds and Foods for Kids (MFK), and in this premiere of the new series, she talks about the important work she does in helping impoverished kids and what a longer life thanks to science would mean. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech #Humanitarianism


Gordan Lauc | Glycans to Prevent Age-Related Diseases
Dec 17 2020 34 mins  
In this presentation given at Ending Age-Related Diseases 2020, Dr. Gordan Lauc of GlycanAge discusses glycans and protein glycosylation, explaining that the glycoproteome is more complex than epigenetics and genetics. He expresses the idea that, as we age, our glycoproteome becomes destabilized and that glycans can be used to return this neglected aspect of aging to a more youthful state. However, as he explains, glycan and glycoproteomic analysis is considerably more difficult than conventional genetic analysis, meaning that significant effort is required in order to properly address this aspect of aging. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech #Glycans #Proteomics #Proteosome


Thomas Weldon | How to Reverse Your Epigenetic Age Now
Dec 16 2020 20 mins  
In this presentation given at Ending Age-Related Diseases 2020, Tom Weldon of Ponce de Leon Health discusses ways in which epigenetic age might be reversed. His company intends to substantially increase human healthspan by using compounds that are generally recognized as safe (GRAS) as a polytherapy, hitting enough aging pathways in order to have a measurable effect in human beings. He presents evidence that his company's flagship product, Rejuvant, has significant positive effects in mice and in people and that this product is being constantly refined for greater effectiveness. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech #Epigenetics #Epigenome #Supplements



Tyler Golato | Molecule: Decentralized Drug Development
Dec 15 2020 25 mins  
In this presentation given at Ending Age-Related Diseases 2020, Dr. Tyler Golato talks about his company, Molecule, highlighting the current problems with pharmaceutical development and offering a new, decentralized method of developing therapies. He discusses the well-known valley of death, the gap between the basic research of academia and the later-stage development of pharmaceutical companies. Dr. Golato advertises Molecule as a method of fostering collaboration between early developers and pharmaceutical companies in order to bridge this gap, particularly in the context of rejuvenation biotechnology. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech #Molecule #Decentralized #Development


Deep Learning Predicts Protein Structure | Lifespan News
Dec 15 2020 9 mins  
SAVE THE DATE! Lifespan News is moving to X10's new channel on January 5, 2021! https://www.youtube.com/lifextenshow ▼▼ Description, sources, and more below ▼▼ In this episode of Lifespan News: 0:00 Intro 0:59 Deep learning predicts protein structure 2:50 CRISPR Successfully Deployed Against Two Cancer Types 4:34 Resveratrol Human Trial Results Published 5:32 Immune Protection for Insulin-Producing Cells 7:32 Linking Alzheimer’s Disease and Gut Bacteria Visit https://youtube.com/BrentNally for more of Brent's content! Executive Producer: Keith Comito Producer: Nicola Bagalà Assistant Producer: Sedeer el-Showk Video Editors: Tim Maupin, Brent Nally Text Editor: Josh Conway SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Deep learning predicts protein structure: https://www.nature.com/articles/d41586-020-03348-4 CRISPR Successfully Deployed Against Two Cancer Types: https://www.lifespan.io/news/crispr-successfully-deployed-against-two-cancer-types/ Resveratrol Human Trial Results Published: https://www.lifespan.io/news/resveratrol-human-trial-results-published/ Immune Protection for Insulin-Producing Cells: https://www.lifespan.io/news/immune-protection-for-insulin-producing-cells/ Linking Alzheimer’s Disease and Gut Bacteria: https://www.lifespan.io/news/linking-alzheimers-disease-and-gut-bacteria/ Steve Hill and Michael Lustgarten on gut bacteria: https://youtu.be/kATDti1sLW8 HOW YOU CAN SUPPORT US ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ If you’d like to help us run this show and/or help Lifespan.io end age-related diseases, you can become a Lifespan Hero: https://lifespan.io/hero. Your support means the world to us! FOLLOW US EVERYWHERE ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Website: https://lifespan.io/lifextenshow Instagram: https://www.instagram.com/lifextenshow/ Facebook: https://www.facebook.com/watch/lifespanio/659351311315977/ Facebook (Lifespan News): https://www.facebook.com/watch/lifespanio/316625179521524/ Twitter: https://twitter.com/lifespanio Discord: https://discord.gg/HwTX7gR FOOTAGE, IMAGES, AND MUSIC CREDITS ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Stock footage: Videoblocks Stock images: Shutterstock Intro music: "Retro 80s technology" by Eric Matyas ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ #AI #AlphaFold #CRISPR #Resveratrol #ClinicalTrials #Insulin #Alzheimers


Kris Verburgh | How to Live Longer? High-Tech and Low-Tech Approaches
Dec 14 2020 52 mins  
In this talk given at Ending Age-Related Diseases 2020, Dr. Kris Verburgh of the Free University of Brussels discusses the methods by which people might lead longer, healthier lives. While some of these methods involve the use of advanced rejuvenation biotechnology techniques, others are simpler to implement and require a minimum amount of technology, such as nutrition and exercise, along with health-monitoring technology that already exists in the public space. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech #Nutrition #Rejuvenation #Lifespan


Hanadie Yousef | Harnessing the Regenerative Secretome of Pluripotent Stem Cells to Rejuvenate
Dec 11 2020 27 mins  
In this presentation given at Ending Age-Related Diseases 2020, Dr. Hanadie Yousef of Juvena Therapeutics discusses the secretome, the signaling system of cells that affect the behavior of other cells. The secretome of embryonic stem cells encourages other cells to grow and develop, proiding a rejuvenative effect. Isolating these proteins and introducing them into aging tissues, therefore, is the basis for a potential suite of therapies for age-related diseases, and Dr. Yousef explains the compounds that could be used for such therapies along with their associated targets. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech


Eric Leire | Genflow Biosciences: A Disruptive Approach to Longevity Therapies
Dec 10 2020 4 mins  
At Ending Age-Related Diseases 2020, Dr. Eric Leire of Genflow Biosciences discussed his company, explaining what Genflow does and how it is funded. The company is intervening directly in the biology of aging, affecting SIRT6, which, like other sirtuins, is a known regulator of aging. The company intends to develop its SIRT6 plasmid as an epigenomic therapy that will affect downstream hallmarks of aging, potentially providing a broad-based solution to multiple age-related diseases. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech



Jonathan Clark | A New Perspective on the Changes in Tendon Collagen Crosslinking With Age
Dec 09 2020 27 mins  
At Ending Age-Related Diseases 2020, Dr. Jonathan Clark of the Babraham Institute gave a presentation on the effects of cross-linked collagen on the elastic deformation of our tendons, which connect muscles and bones. The conventional wisdom is that as we age, our tendons lose the ability to stretch, but Dr. Clark presents evidence offering a new perspective on this idea while showing how the collagen is becoming more fragile. He shows the various compounds that cause collagen to irreversibly cross-link, including glucosepane, and he shows that one reversible, enzymatic cross-link, HLNL, actually sharply decreases with age. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech


Alexey Moskalev | Genetic Mechanisms of Aging in the Drosophila Model
Dec 08 2020 8 mins  
At Ending Age-Related Diseases 2020, Dr. Alexey Moskalev gave a presentation on Drosophila genetics. While it is not a mammal and certainly not a human being, Drosophila is a common subject for aging research, as it is a short-lived insect that shares many of the same aging-related genetic pathways as larger animals. Here, Dr. Moskalev shows that the carotenoid fucoxanthin affects these pathways, lengthening these flies' lifespan and reducing their intestinal permeability, a biomarker of aging for these flies. He goes into detail when discussing the genes involved, providing a very thorough overview of how they work. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech


Avoiding Osteoporosis with Alpha-Ketoglutarate | Lifespan News
Dec 08 2020 9 mins  
Lifespan News is moving to X10's new channel! https://www.youtube.com/lifextenshow ▼▼ Description, sources, and more below ▼▼ In this episode of Lifespan News: 0:00 Intro 1:03 Elevian Secures $15 Million in Equity Financing 2:18 Avoiding Osteoporosis with Alpha-Ketoglutarate 3:55 A New Scaffolding For Liver Cell Cultures 5:28 Gene Discovered to Alleviate Obesity 7:13 ‘Healthy Longevity For All’ Wins The Vote For The Global Health Reset Visit https://youtube.com/BrentNally for more of Brent's content! Executive Producer: Keith Comito Producer: Nicola Bagalà Assistant Producer: Sedeer el-Showk Video Editors: Tim Maupin, Brent Nally Text Editor: Josh Conway SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Elevian Secures $15 Million in Equity Financing: https://www.lifespan.io/news/elevian-secures-15-million-in-equity-financing/ Avoiding Osteoporosis with Alpha-Ketoglutarate: https://www.lifespan.io/news/avoiding-osteoporosis-with-alpha-ketoglutarate/ The Sheekey Science Show on this topic: https://www.youtube.com/watch?v=schpStkK0tk A New Scaffolding For Liver Cell Cultures: https://www.lifespan.io/news/a-new-scaffold-for-liver-regeneration/ Gene Discovered to Alleviate Obesity https://www.lifespan.io/news/gene-discovered-to-alleviate-obesity/ ‘Healthy Longevity For All’ Wins The Vote For The Global Health Reset https://www.forbes.com/sites/tinawoods/2020/11/18/healthy-longevity-for-all-wins-the-vote-for-the-global-health-reset/ HOW YOU CAN SUPPORT US ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ If you’d like to help us run this show and/or help Lifespan.io end age-related diseases, you can become a Lifespan Hero: https://lifespan.io/hero. Your support means the world to us! FOLLOW US EVERYWHERE ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Website: https://lifespan.io/lifextenshow Instagram: https://instagram.com/lifespanio Facebook: https://facebook.com/lifespanio Twitter: https://twitter.com/lifespanio Discord: https://discord.gg/HwTX7gR FOOTAGE, IMAGES, AND MUSIC CREDITS ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Intro music: "Retro 80s technology" by Eric Matyas ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ #osteoporosis #aging #obesity #liver #GDF11 #covid19


Judith Campisi | Targeting Senescent Cells to Alleviate Aging: A Simple Task?
Dec 07 2020 26 mins  
At Ending Age-Related Diseases 2020, Prof. Judith Campisi of the Buck Institute for Research on Aging discussed the effects and usage of senolytics, drugs that remove senescent cells from the body. She went into the details of the stress and damage signals that cause cells to become senescent and the markers of senescent cells, noting that no marker is specific to senescence. She also discussed the senescence-associated secretory phenotype (SASP), which causes other cells to become senescent. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech


Gabriela Bunu | SynergyAge: A Curated Database for Interactions of Longevity Genes
Dec 04 2020 11 mins  
At Ending Age-Related Diseases 2020, Gabriela Bunu of the Institute of Biochemistry, Romanian Academy discusses SynergyAge, a database of the interactions of longevity-associated genes. This database is designed to calculate which genes are responsible for longevity, and which genes have been associated with a lack of longevity, in several distinct organisms, including mice. Multiple biochemical pathways were addressed, including the mTOR pathway and autophagy. Most notably, many of these genes had a synergistic effect, showing the combinations of expressed proteins that are most fruitful in extending lifespan. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech



Alexander Fedintsev | Collagen Glycation: Beyond Vascular Stiffness and Hypertension
Dec 03 2020 13 mins  
At Ending Age-Related Diseases 2020, Dr. Alexander Fedintsev of the Institute of Biology of FRC of Komi Scientific Center, RAS gave a talk about collagen glycation. Cross-links caused by advanced glycation end-products such as glucosepane stiffen the extracellular matrix, leading to systemic problems. Dr. Fedintsev provides evidence showing that the stiffened ECM leads to stem cell depletion, cellular senescence, and the failure of neurons to form synapses. If this glycation can be reversed, it could lead to a partial reversal of these elements of aging. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech


Polina Mamoshina | Deep Biomarkers of Human Aging
Dec 02 2020 25 mins  
At Ending Age-Related Diseases 2020, Dr. Polina Mamoshina of Insilico Medicine gave a talk on the subject of biomarkers of human aging that are generated through deep learning algorithms. Deep learning, an advancement over older algorithms of artificial intelligence, has allowed for the useful collection of various data, including facial analysis, bone x-rays, blood markers, and brain MRIs. Individually, each of these biomarkers may be slightly inaccurate, but they are even more effective when combined, thus providing a useful analysis tool for human aging and ways in which it can be treated. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech


Rejuvenation Roundup November 2020
Dec 01 2020 17 mins  
This month on the Rejuvenation Roundup Podcast, Ryan O'Shea of Future Grind talks about Lifespan.io president Keith Comito's appearance at the Eurosymposium on Healthy Aging, Science to Save the World's episode on sleep and Alzheimer's, blood factors and aging, a gene that protects against negative effects of obesity, resveratrol's effects against heart disease, lung organoids and the pandemic, and other rejuvenation topics. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO NEWS & SOCIAL MEDIA ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ News: https://www.lifespan.io/news Facebook: https://www.lifespan.io/facebook Instagram: https://www.lifespan.io/instagram LinkedIn: https://www.lifespan.io/linkedin Twitter: https://www.lifespan.io/twitter Discord: https://www.lifespan.io/discord Newsletter: https://www.lifespan.io/newsletter YOUTUBE COLLABORATIONS: ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Kurzgesagt: https://www.youtube.com/watch?v=MjdpR-TY6QU Life Noggin: https://www.youtube.com/watch?v=EEO4bHbxRgo TOOLS & RESOURCES ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Research Roadmap: https://www.lifespan.io/roadmap Investor Network: https://www.lifespan.io/investor Journal Club: https://www.lifespan.io/journalclub Conferences: https://www.lifespan.io/conference MORE INFO ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Age-related diseases, such as Alzheimer's, heart disease, and cancer, are some of the worst drains on our society, both in terms of personal suffering and socio-economic effects. One of the reasons why our work is so important is that, historically, research aimed at tackling these diseases has been focused at the end stages of such maladies, when it is too late to reverse the damage that has been done. A good analogy is a tree: what makes more sense — spending a ton of money trying to cure a branch of a branch, or directing that focus to the trunk of the tree itself? Aging is the greatest risk factor for all of these major diseases, and in many cases, it is ultimately the primary cause. While it may seem hard to believe, biological science has finally progressed enough to begin targeting the root mechanisms of aging, and — thanks to the efforts of the world-renowned researchers and labs we work with, such as Drs. David Sinclair, George Church, and Aubrey de Grey — is beginning to bring aging, and therefore these diseases, under medical control. Everything we've done thus far, and everything we will do in the future, is thanks to your support, and that is why we are asking you to stand with us - to be a Lifespan Hero and help us improve the lives of not just ourselves and our family members, but everyone in the entire world. Together, we can do this. Be a Hero. JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech


Hyperbaric Oxygen Therapy, Telomere Length, and Immunosenescence | Lifespan News
Dec 01 2020 9 mins  
Lifespan News is moving to X10's new channel! https://www.youtube.com/lifextenshow ▼▼ Description, sources, and more below ▼▼ In this episode of Lifespan News: 0:00 Intro 1:07 Hyperbaric Oxygen Therapy, Telomere Length, and Immunosenescence 2:19 New Course to Teach Doctors About Longevity Medicine 3:27 Inflammation Decreases NAD+ During Aging 5:07 Diluting Aged Blood Rejuvenates Old Brains 6:52 Longevity Dialogues – Featuring Dr. Aubrey de Grey, Dr. Nir Barzilai and Keith Comito Visit https://youtube.com/BrentNally for more of Brent's content! Executive Producer: Keith Comito Producer: Nicola Bagalà Assistant Producer: Sedeer el-Showk Video Editors: Tim Maupin, Brent Nally Text Editor: Josh Conway SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Hyperbaric Oxygen Therapy, Telomere Length, and Immunosenescence: https://www.aging-us.com/article/202188/text https://www.lifespan.io/news/media-circus-surrounds-hyperbaric-oxygen-study/ The Sheekey Science Show on this story: https://www.youtube.com/watch?v=623pUvhnMGE New Course to Teach Doctors About Longevity Medicine: https://www.lifespan.io/news/new-course-to-teach-doctors-about-longevity-medicine/ Deep Longevity: https://deeplongevity.com/ Longevity Medicine Course: https://www.longevity-medicine.org/ Inflammation Decreases NAD+ During Aging: https://www.lifespan.io/news/inflammation-decreases-nad-during-aging/ Study: https://www.nature.com/articles/s42255-020-00305-3 Diluting Aged Blood Rejuvenates Old Brains: https://www.lifespan.io/news/diluting-aged-blood-rejuvenates-old-brains/ New study: https://link.springer.com/article/10.1007/s11357-020-00297-8 Previous study by the Conboy Lab: https://www.aging-us.com/article/103418/text Longevity Dialogues – Featuring Dr. Aubrey de Grey, Dr. Nir Barzilai and Keith Comito: https://www.lifespan.io/news/longevity-dialogues-selling-the-science/ Seeking Delphi: https://seekingdelphi.com/ The latest Longevity Dialogues episode: https://youtu.be/dkJj33Wj7f8 HOW YOU CAN SUPPORT US ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ If you’d like to help us run this show and/or help Lifespan.io end age-related diseases, you can become a Lifespan Hero: https://lifespan.io/hero. Your support means the world to us! FOLLOW US EVERYWHERE ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Website: https://lifespan.io/lifextenshow Instagram: https://instagram.com/lifespanio Facebook: https://facebook.com/lifespanio Twitter: https://twitter.com/lifespanio Discord: https://discord.gg/HwTX7gR FOOTAGE, IMAGES, AND MUSIC CREDITS ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Intro music: "Retro 80s technology" by Eric Matyas ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ #Aging #Longevity #Medicine #NAD #Inflammation #Blood #Mice #SeekingDelphi #WebSeries


Steve Horvath | Epigenetic Clocks for Clinical and Preclinical Applications
Dec 01 2020 24 mins  
Dr. Steve Horvath is very well known in the field for his groundbreaking work on epigenetic clocks, which use one of the hallmarks of aging, epigenetic alterations, in order to calculate biological age. In his talk at Ending Age-Related Diseases 2020, he discusses how such clocks can be used to evaluate the effectiveness of rejuvenation biotechnology therapies, providing useful clinical endpoints that don't involve waiting for people to age and die. In collaboration with other researchers, he recently published a scientific paper on this topic, and our discussion of it is available at https://www.lifespan.io/news/grimage-is-the-best-clock-for-predicting-death/ HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech





Michael Lustgarten and Steve Hill on the Effects of the Microbiome on Alzheimer's Disease
Nov 27 2020 36 mins  
Today, Michael Lustgarten talks with Steve Hill about the gut microbiome, which consists of the bacteria that live in our intestines, and its effects on amyloid formation. Butyrate is a beneficial compound produced by such bacteria, but other bacteria produce compounds that are not so beneficial. Read more about the microbiome and how it affects amyloids at https://www.lifespan.io/news/linking-alzheimers-disease-and-gut-bacteria/ Professor Lustgarten's website is at https://michaellustgarten.com/ and his YouTube channel can be found at https://www.youtube.com/channel/UCT1UMLpZ_CrQ_8I431K0b-g/featured HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech


Using lung organoids to study COVID
Nov 24 2020 8 mins  
Lifespan News is moving to X10's new channel! https://www.youtube.com/lifextenshow ▼▼ Description, sources, and more below ▼▼ In this episode of Lifespan News: 0:00 Intro 1:29 2020 Century Summit 2:13 Aged blood ages gene expression 3:43 Using lung organoids to study COVID 5:02 OneSkin Has Released a Senotherapeutic Skin Cream 6:33 New book about AI and longevity SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ 2020 Century Summit: https://longevity.stanford.edu/century-summit/ Aged blood ages gene expression: https://www.lifespan.io/news/aged-blood-causes-gene-expression-to-age/ Using lung organoids to study COVID: https://www.lifespan.io/news/researchers-use-lung-organoids-to-study-covid/ OneSkin Has Released a Senotherapeutic Skin Cream: https://www.lifespan.io/news/oneskin-has-released-a-senotherapeutic-skin-cream/ Preprint paper: https://www.biorxiv.org/content/10.1101/2020.10.30.362822v2 New book about AI and longevity: https://www.lifespan.io/news/ai-and-longevity-meet-in-a-new-book/ Cell Visualization and VR on StStW: https://www.youtube.com/watch?v=003zP6uBNBY HOW YOU CAN SUPPORT US ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ If you’d like to help us run this show and/or help Lifespan.io end age-related diseases, you can become a Lifespan Hero: https://lifespan.io/hero. Your support means the world to us! FOOTAGE, IMAGES, AND MUSIC CREDITS ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Intro music: "Retro 80s technology" by Eric Matyas FOLLOW US EVERYWHERE ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Website: https://lifespan.io/lifextenshow Instagram: https://instagram.com/lifespanio Facebook: https://facebok.com/lifespanio Twitter: https://twitter.com/lifespanio Discord: https://discord.gg/HwTX7gR ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ #COVID19 #organoids #longevity #conferences #aging #blood #geneexpression #skincreams #senolytics #books #AI


The Extracellular Matrix Is Key to Heart Health | Lifespan News
Nov 17 2020 7 mins  
Lifespan News is moving to X10's new channel! https://www.youtube.com/lifextenshow ▼▼ Description, sources, and more below ▼▼ In this episode of Lifespan News: 0:00 Intro 1:04 WHO launches aging portal 1:59 Breanna Deutsch Wants You to Contact Lawmakers About Aging 2:43 The Extracellular Matrix Is Key to Heart Health 4:28 C60 Does Not Improve Lifespan or Healthspan 5:58 Dr. Matt Kaeberlein on the NUS longevity webinar SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ WHO launches aging portal: https://www.who.int/data/maternal-newborn-child-adolescent-ageing/ageing-data Breanna Deutsch Wants You to Contact Lawmakers About Aging: https://www.lifespan.io/news/breanna-deutsch-wants-you-to-contact-lawmakers-about-aging/ Book review: https://www.lifespan.io/news/breanna-deutsch-explains-how-to-find-the-fountain/ The Extracellular Matrix Is Key to Heart Health: https://www.lifespan.io/news/the-extracellular-matrix-is-key-to-heart-health/ C60 Does Not Improve Lifespan or Healthspan: https://www.lifespan.io/news/c60-does-not-improve-lifespan-nor-healthspan/ C60 on The Sheekey Science Show: https://www.youtube.com/watch?v=ntEELRfE1Oc Subscribe to Eleanor's channel: https://www.youtube.com/c/TheSheekeyScienceShow?sub_confirmation=1 Dr. Matt Kaeberlein on the NUS longevity webinar https://www.youtube.com/watch?v=KhWHXU0GTOA HOW YOU CAN SUPPORT US ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ If you’d like to help us run this show and/or help Lifespan.io end age-related diseases, you can become a Lifespan Hero: https://lifespan.io/hero. Your support means the world to us! FOLLOW US EVERYWHERE ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Website: https://lifespan.io/lifextenshow Instagram: https://instagram.com/lifespanio Facebook: https://facebok.com/lifespanio Twitter: https://twitter.com/lifespanio Discord: https://discord.gg/HwTX7gR ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ #Aging #WHO #ECM #Biology #BuckyBalls #NUS #DogAgingProject #GrassrootsLongevity


Breanna Deutsch Explains How to Find the Fountain | Lifespan News
Nov 10 2020 7 mins  
Lifespan News is moving to X10's new channel! https://www.youtube.com/lifextenshow ▼▼ Description, sources, and more below ▼▼ In this episode of Lifespan News: 0:00 Intro 0:38 Partial Cellular Reprogramming Improves Memory in Old Mice 1:45 Metformin and Resistance Training: Downside and Upside 3:13 Breanna Deutsch Explains How to Find the Fountain 4:06 Cartilage Regeneration Accomplished in Vitro 5:50 Women’s telomere length correlates with their age at the birth of their last child SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Partial Cellular Reprogramming Improves Memory in Old Mice: https://www.lifespan.io/news/partial-cellular-reprogramming-improves-memory-in-old-mice/ Metformin and Resistance Training: Downside and Upside: https://www.lifespan.io/news/metformin-and-resistance-training-downside-and-upside/ Study: https://www.aging-us.com/article/104096/text Breanna Deutsch Explains How to Find the Fountain: https://www.lifespan.io/news/breanna-deutsch-explains-how-to-find-the-fountain/ Cartilage Regeneration Accomplished in Vitro: https://www.lifespan.io/news/cartilage-regeneration-accomplished-in-vitro/ Study: https://dx.doi.org/10.1186%2Fs13287-020-01930-1 Women’s telomere length correlates with their age at the birth of their last child: https://journals.lww.com/menopausejournal/Abstract/2020/11000/Maternal_age_at_last_birth_and_leukocyte_telomere.9.aspx HOW YOU CAN SUPPORT US ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ If you’d like to help us run this show and/or help Lifespan.io end age-related diseases, you can become a Lifespan Hero: https://lifespan.io/hero. Your support means the world to us! FOLLOW US EVERYWHERE ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Website: https://lifespan.io/lifextenshow Instagram: https://instagram.com/lifespanio Facebook: https://facebok.com/lifespanio Twitter: https://twitter.com/lifespanio Discord: https://discord.gg/HwTX7gR ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ #OSKM #Doxycycline #Memory #Metformin #PRT #Books #BreannaDeutsch #Cartilage #RegenerativeMedicine #Telomeres



Ending Age-Related Diseases 2020 Panel: How to Overcome the Valley of Death in Biotech Development?
Nov 06 2020 43 mins  
At this panel from Ending Age-Related Diseases 2020, Javier Noris of Lifespan.io talks with Patrick Burgermeister of Kizoo Ventures, Reason of Repair Biotechnologies, Sergio Ruiz of Methuselah Labs, and Ronjon Nag of Institute R42 about the valley of death in biotech investment. Early-stage research is funded by universities and governments, and companies are funded by investors, but it is difficult for researchers to bring their findings to the level at which investors would be interested, and being unable to cross this valley of death is a significant hindrance for the development of rejuvenation biotechnology. Being able to reliably overcome this would be a major benefit for the development of therapies that directly target the root causes of aging. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech


Keith Comito | EHA 2020 | Biomarkers, Data Standardization, and Unlocking the Longevity Dividend
Nov 06 2020 15 mins  
At the Eurosymposium on Healthy Aging 2020, Lifespan.io president Keith Comito discusses how to take lessons from other fields in generating, storing, and using biomarker data systems in order to provide useful information on aging at both the personal and the population levels. This information is currently not standardized, and this makes it difficult to use these biomarkers effectively. Creating formalized standards would allow people to more effectively use this information. Bringing in multiple stakeholders, from corporations to government, would pave the way for a unified push for longevity. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech


Fighting Cancer With CRISPR | Lifespan News
Nov 03 2020 7 mins  
Lifespan News is moving to X10's new channel! https://www.youtube.com/lifextenshow ▼▼ Description, sources, and more below ▼▼ In this episode of Lifespan News: 0:00 Intro 0:37 The Lancet launches longevity journal 1:14 Fighting cancer with CRISPR 2:02 A new mechanism of telomere lengthening in T cells discovered 3:19 Generating Neural Progenitor Cells from iPSCs 4:30 A Genetic Footprint of Aging SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ The Lancet launches longevity journal: https://www.thelancet.com/lanhl/about The Lancet's new journal's editorial: https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(20)30022-2/fulltext Fighting cancer with CRISPR: https://www.lifespan.io/news/using-crispr-to-remove-mutated-dna-to-defeat-cancer/ A New Mechanism of Telomere Lengthening in T Cells Discovered: https://www.lifespan.io/news/a-new-mechanism-of-telomere-lengthening-in-t-cells-discovered/ Generating Neural Progenitor Cells from iPSCs: https://www.lifespan.io/news/generating-neural-progenitor-cells-from-ipscs/ Study: https://doi.org/10.1002/term.3143 A Genetic Footprint of Aging: https://www.lifespan.io/news/a-genetic-footprint-of-aging/ HOW YOU CAN SUPPORT US ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ If you’d like to help us run this show and/or help Lifespan.io end age-related diseases, you can become a Lifespan Hero: https://lifespan.io/hero. Your support means the world to us! FOLLOW US EVERYWHERE ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Website: https://lifespan.io/lifextenshow Instagram: https://instagram.com/lifespanio Facebook: https://facebok.com/lifespanio Twitter: https://twitter.com/lifespanio Discord: https://discord.gg/HwTX7gR ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ #TheLancet #Aging #Cancer #CRISPR #Telomeres #iPSCs #RegenerativeMedicine #Genetics


Rejuvenation Roundup October 2020
Nov 03 2020 17 mins  
This month on the Rejuvenation Roundup Podcast, Ryan O'Shea of Future Grind talks about confidence in institutions and ranked choice voting, liquid democracy, Ending Age-Related 2020 videos, sirtuin genes such as SIRT1 and cellular senescence, the LEF1 gene and skin regeneration, CRISPR that directly attacks cancer, metformin interfering with muscle hypertrophy but enhancing youthful gene expression, and the All Party Parliamentary Group's efforts in promoting healthy longevity in the UK. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO NEWS & SOCIAL MEDIA ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ News: https://www.lifespan.io/news Facebook: https://www.lifespan.io/facebook Instagram: https://www.lifespan.io/instagram LinkedIn: https://www.lifespan.io/linkedin Twitter: https://www.lifespan.io/twitter Discord: https://www.lifespan.io/discord Newsletter: https://www.lifespan.io/newsletter YOUTUBE COLLABORATIONS: ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Kurzgesagt: https://www.youtube.com/watch?v=MjdpR-TY6QU Life Noggin: https://www.youtube.com/watch?v=EEO4bHbxRgo TOOLS & RESOURCES ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Research Roadmap: https://www.lifespan.io/roadmap Investor Network: https://www.lifespan.io/investor Journal Club: https://www.lifespan.io/journalclub Conferences: https://www.lifespan.io/conference MORE INFO ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Age-related diseases, such as Alzheimer's, heart disease, and cancer, are some of the worst drains on our society, both in terms of personal suffering and socio-economic effects. One of the reasons why our work is so important is that, historically, research aimed at tackling these diseases has been focused at the end stages of such maladies, when it is too late to reverse the damage that has been done. A good analogy is a tree: what makes more sense — spending a ton of money trying to cure a branch of a branch, or directing that focus to the trunk of the tree itself? Aging is the greatest risk factor for all of these major diseases, and in many cases, it is ultimately the primary cause. While it may seem hard to believe, biological science has finally progressed enough to begin targeting the root mechanisms of aging, and — thanks to the efforts of the world-renowned researchers and labs we work with, such as Drs. David Sinclair, George Church, and Aubrey de Grey — is beginning to bring aging, and therefore these diseases, under medical control. Everything we've done thus far, and everything we will do in the future, is thanks to your support, and that is why we are asking you to stand with us - to be a Lifespan Hero and help us improve the lives of not just ourselves and our family members, but everyone in the entire world. Together, we can do this. Be a Hero. JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech







A New Senolytic Enters Human Trials | Lifespan News
Oct 27 2020 7 mins  
Lifespan News is moving to X10's new channel! https://www.youtube.com/lifextenshow ▼▼ Description, sources, and more below ▼▼ In this episode of Lifespan News: 0:00 Intro 0:37 Regenerating Skin With a Single Protein 1:27 A New Senolytic Enters Human Trials 2:27 T Cell Progenitors Boost Stem Cell Therapy Effectiveness 4:24 Creating Anti-Glucosepane Antibodies 5:41 Big pharma enters senolytic drug discovery program Visit https://youtube.com/BrentNally for more of Brent's content! Executive Producer: Keith Comito Producer: Nicola Bagalà Assistant Producer: Sedeer el-Showk Video Editors: Tim Maupin, Brent Nally Text Editor: Josh Conway SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Regenerating Skin With a Single Protein: https://www.lifespan.io/news/regenerating-skin-with-a-single-protein/ https://scitechdaily.com/genetic-factor-discovery-enables-adult-skin-to-regenerate-like-a-newborn-babys/ https://skinregeneration.org/ A New Senolytic Enters Human Trials: https://www.lifespan.io/news/a-new-senolytic-enters-human-trials/ T Cell Progenitors Boost Stem Cell Therapy Effectiveness: https://www.lifespan.io/news/t-cell-progenitors-boost-stem-cell-therapy-effectiveness/ Creating Anti-Glucosepane Antibodies: https://www.lifespan.io/news/creating-anti-glucosepane-antibodies/ Big pharma enters senolytic drug discovery program: https://www.longevity.technology/big-pharma-enters-senolytic-drug-discovery-programme/ HOW YOU CAN SUPPORT US ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ If you’d like to help us run this show and/or help Lifespan.io end age-related diseases, you can become a Lifespan Hero: https://lifespan.io/hero. Your support means the world to us! FOLLOW US EVERYWHERE ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Website: https://lifespan.io/lifextenshow Instagram: https://instagram.com/lifespanio Facebook: https://facebok.com/lifespanio Twitter: https://twitter.com/lifespanio Discord: https://discord.gg/HwTX7gR ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ #Skin #Type2Diabetes #SenescentCells #ClinicalTrials #Cancer #ImmuneSystem #Glucosepane #AI #Insilico




Today’s Elderly Are Healthier Than a Generation Ago | Lifespan News
Oct 20 2020 6 mins  
Lifespan News is moving to X10's new channel! https://www.youtube.com/lifextenshow ▼▼ Description, sources, and more below ▼▼ In this episode of Lifespan News: 0:00 Intro 0:37 Today’s Elderly Are Healthier Than a Generation Ago 1:52 A New Atlas of Dental Cells 2:33 Grant enables psychologists to extend research on behavioural aging and cognitive development 3:37 Medin Aggregates Cause Cerebrovascular Dysfunction in Mice 4:24 Senescent Cells Have Less SIRT1 as a Result of Autophagy Visit https://youtube.com/BrentNally for more of Brent's content! Executive Producer: Keith Comito Producer: Nicola Bagalà Assistant Producer: Sedeer el-Showk Video Editors: Tim Maupin, Brent Nally Text Editor: Josh Conway SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Today’s Elderly Are Healthier Than a Generation Ago: https://www.lifespan.io/news/todays-elderly-are-healthier-than-a-generation-ago/ A New Atlas of Dental Cells: https://www.lifespan.io/news/a-new-atlas-of-dental-cells/ Grant enables psychologists to extend research on behavioural aging and cognitive development: https://www.eurekalert.org/pub_releases/2020-09/uoc--gfr092420.php Medin Aggregates Cause Cerebrovascular Dysfunction in Mice: https://www.lifespan.io/news/medin-aggregates-cause-cerebrovascular-dysfunction-in-mice/ Senescent Cells Have Less SIRT1 as a Result of Autophagy: https://www.lifespan.io/news/senescent-cells-have-less-sirt1-as-a-result-of-autophagy/ HOW YOU CAN SUPPORT US ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ If you’d like to help us run this show and/or help Lifespan.io end age-related diseases, you can become a Lifespan Hero: https://lifespan.io/hero. Your support means the world to us! FOLLOW US EVERYWHERE ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Website: https://lifespan.io/lifextenshow Instagram: https://instagram.com/lifespanio Facebook: https://facebok.com/lifespanio Twitter: https://twitter.com/lifespanio Discord: https://discord.gg/HwTX7gR ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ #Aging #Health #Teeth #Psychology #CerebrovascularDiseases #SenescentCells #SIRT1









Rick Kiessig Discusses VTose, a Broad-Spectrum Antiviral | Lifespan News
Oct 13 2020 7 mins  
Lifespan News is moving to X10's new channel! https://www.youtube.com/lifextenshow ▼▼ Description, sources, and more below ▼▼ In this episode of Lifespan News: 0:00 Intro 0:38 New Perks for Lifespan Heroes! 1:21 Nanoparticles with Self-Replicating RNA Stop Cancer in Mice 3:31 Rick Kiessig Discusses VTose, a Broad-Spectrum Antiviral 4:28 Enhancing blood sugar control boosts brain health for people with type 2 diabetes 5:44 Plant Flavonoid Naringenin Is a Senotherapeutic Visit https://youtube.com/BrentNally for more of Brent's content! Executive Producer: Keith Comito Producer: Nicola Bagalà Assistant Producer: Sedeer el-Showk Video Editors: Tim Maupin, Brent Nally Text Editor: Josh Conway SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ New Perks for Lifespan Heroes: https://www.lifespan.io/news/new-perks-for-lifespan-heroes/ Nanoparticles with Self-Replicating RNA Stop Cancer in Mice: https://www.lifespan.io/news/nanoparticles-with-self-replicating-rna-stop-cancer-in-mice/ https://www.nature.com/articles/s43018-020-0095-6- Rick Kiessig Discusses VTose, a Broad-Spectrum Antiviral: https://www.lifespan.io/news/rick-kiessig-discusses-vtose-a-broad-spectrum-antiviral/ Enhancing blood sugar control boosts brain health for people with type 2 diabetes: https://medicalxpress.com/news/2020-10-blood-sugar-boosts-brain-health.html Plant Flavonoid Naringenin Is a Senotherapeutic: https://www.lifespan.io/news/plant-flavonoid-naringenin-is-a-senotherapeutic/ https://www.aging-us.com/article/103955/text HOW YOU CAN SUPPORT US ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ If you’d like to help us run this show and/or help Lifespan.io end age-related diseases, you can become a Lifespan Hero: https://lifespan.io/hero. Your support means the world to us! FOLLOW US EVERYWHERE ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Website: https://lifespan.io/lifextenshow Instagram: https://instagram.com/lifespanio Facebook: https://facebok.com/lifespanio Twitter: https://twitter.com/lifespanio Discord: https://discord.gg/HwTX7gR ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ #LifespanIO #Cancer #Immunotherapy #RNA #Viruses #Antivirals #Type2Diabetes #Obesity #Senolytics #CellSenescence


Elena Milova Interviews Mair Underwood on Public Perception of Life Extension
Oct 12 2020 29 mins  
In this interview at Ending Age-Related Diseases 2020, Elena Milova of Lifespan.io and Dr. Mair Underwood of the University of Queensland discuss the societal factors that lead to the public perception of rejuvenation biotechnology, including traditional views of the human body and modern views on human alteration, and Dr. Underwood highlights the various thought processes and moral structures that lead to opposition to the idea of extending human lifespan and healthspan. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech


Young.ai - artificial intelligence for tracking aging in humans | Lifespan News
Oct 06 2020 7 mins  
Lifespan News is moving to X10's new channel! https://www.youtube.com/lifextenshow ▼▼ Description, sources, and more below ▼▼ In this episode of Lifespan News: 0:00 Intro 0:38 Young.ai - artificial intelligence for tracking aging in humans 1:35 A Link Between the Microbiome, Heat, and Osteoporosis 2:34 Age-Related Female Fertility Decline Linked to Mitochondrial Mutation 4:14 A New Microporous Membrane for Skin Regeneration 5:13 Microtubule Stabilization Ameliorates Alzheimer’s Symptoms in Mice Visit https://youtube.com/BrentNally for more of Brent's content! Executive Producer: Keith Comito Producer: Nicola Bagalà Assistant Producer: Sedeer el-Showk Video Editors: Tim Maupin, Brent Nally Text Editor: Josh Conway SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Young.ai - artificial intelligence for tracking aging in humans: https://www.eurekalert.org/pub_releases/2020-09/dll-dlr092120.php A Link Between the Microbiome, Heat, and Osteoporosis: https://www.lifespan.io/news/a-link-between-the-microbiome-heat-and-osteoporosis/ Age-Related Female Fertility Decline Linked to Mitochondrial Mutation: https://www.lifespan.io/news/age-related-female-fertility-decline-linked-to-mitochondrial-mutation/ A New Microporous Membrane for Skin Regeneration: https://www.lifespan.io/news/a-new-microporous-membrane-for-skin-regeneration/ Microtubule Stabilization Ameliorates Alzheimer’s Symptoms in Mice: https://www.lifespan.io/news/microtubule-stabilization-ameliorates-alzheimers-symptoms-in-mice/ HOW YOU CAN SUPPORT US ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ If you’d like to help us run this show and/or help Lifespan.io end age-related diseases, you can become a Lifespan Hero: https://lifespan.io/hero. Your support means the world to us! FOLLOW US EVERYWHERE ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Website: https://lifespan.io/lifextenshow Instagram: https://instagram.com/lifespanio Facebook: https://facebok.com/lifespanio Twitter: https://twitter.com/lifespanio Discord: https://discord.gg/HwTX7gR ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ #AI #Aging #Microbiome #Osteoporosis #Fertility #Mitochondria #Skin #Alzheimers





Rejuvenation Roundup September 2020
Oct 01 2020 18 mins  
This month on the Rejuvenation Roundup Podcast, Ryan O'Shea of Future Grind talks about Lifespan.io's new writer, Lifespan News discussing the effects of alpha-ketoglutarate on lifespan and healthspan, Science to Save the World, the positive effects of caloric restriction on DNA repair, epigenetic clocks, the effects of temperature on osteoporosis, and other rejuvenation topics. HOW CAN YOU SUPPORT US? ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ LEAF / Lifespan.io is a 501(c)(3) nonprofit organization. Everything we've done thus far and everything we will do in the future is thanks to your support - please stand with us to fight the diseases of aging and increase healthy human lifespan. ► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero ► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support ► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io ► Subscribe: http://www.youtube.com/user/LifespanIO NEWS & SOCIAL MEDIA ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ News: https://www.lifespan.io/news Facebook: https://www.lifespan.io/facebook Instagram: https://www.lifespan.io/instagram LinkedIn: https://www.lifespan.io/linkedin Twitter: https://www.lifespan.io/twitter Discord: https://www.lifespan.io/discord Newsletter: https://www.lifespan.io/newsletter YOUTUBE COLLABORATIONS: ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Kurzgesagt: https://www.youtube.com/watch?v=MjdpR-TY6QU Life Noggin: https://www.youtube.com/watch?v=EEO4bHbxRgo TOOLS & RESOURCES ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Research Roadmap: https://www.lifespan.io/roadmap Investor Network: https://www.lifespan.io/investor Journal Club: https://www.lifespan.io/journalclub Conferences: https://www.lifespan.io/conference MORE INFO ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Age-related diseases, such as Alzheimer's, heart disease, and cancer, are some of the worst drains on our society, both in terms of personal suffering and socio-economic effects. One of the reasons why our work is so important is that, historically, research aimed at tackling these diseases has been focused at the end stages of such maladies, when it is too late to reverse the damage that has been done. A good analogy is a tree: what makes more sense — spending a ton of money trying to cure a branch of a branch, or directing that focus to the trunk of the tree itself? Aging is the greatest risk factor for all of these major diseases, and in many cases, it is ultimately the primary cause. While it may seem hard to believe, biological science has finally progressed enough to begin targeting the root mechanisms of aging, and — thanks to the efforts of the world-renowned researchers and labs we work with, such as Drs. David Sinclair, George Church, and Aubrey de Grey — is beginning to bring aging, and therefore these diseases, under medical control. Everything we've done thus far, and everything we will do in the future, is thanks to your support, and that is why we are asking you to stand with us - to be a Lifespan Hero and help us improve the lives of not just ourselves and our family members, but everyone in the entire world. Together, we can do this. Be a Hero. JOIN US ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Join us, and together, we can overcome diseases like Alzheimer's, heart disease, and cancer by addressing their shared source: the aging processes themselves. #Research #Aging #Funding #LEAF #Biotech


An epigenetic clock for cats | Lifespan News
Sep 29 2020 6 mins  
Lifespan News is moving to X10's new channel! https://www.youtube.com/lifextenshow ▼▼ Description, sources, and more below ▼▼ In this episode of Lifespan News: 0:00 Intro 0:39 An epigenetic clock for cats 1:35 Elite athletes have greater epigenetic age 2:52 A two-pronged approach to bone repair 3:42 Caloric restriction improves DNA repair in mice 4:50 A new research center to study aging Visit https://youtube.com/BrentNally for more of Brent's content! Executive Producer: Keith Comito Producer: Nicola Bagalà Assistant Producer: Sedeer el-Showk Video Editors: Tim Maupin, Brent Nally Text Editor: Josh Conway SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ An epigenetic clock for cats: https://www.lifespan.io/news/methylation-clocks-that-measure-the-biological-age-of-cats/ Elite athletes have greater epigenetic age: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842850/ A two-pronged approach to bone repair: https://www.lifespan.io/news/bmp4-and-vegf-promote-bone-regeneration/ Caloric restriction improves DNA repair in mice: https://www.lifespan.io/news/caloric-restriction-improves-dna-repair-in-mice/ A new research center to study aging: https://www.eurekalert.org/pub_releases/2020-09/si-tsd091620.php HOW YOU CAN SUPPORT US ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ If you’d like to help us run this show and/or help Lifespan.io end age-related diseases, you can become a Lifespan Hero: https://lifespan.io/hero. Your support means the world to us! FOLLOW US EVERYWHERE ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Website: https://lifespan.io/lifextenshow Instagram: https://instagram.com/lifespanio Facebook: https://facebook.com/lifespanio Twitter: https://twitter.com/lifespanio Discord: https://discord.gg/HwTX7gR ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ #Epigenetics #Cats #Aging #Athletes #BoneRepair #CaloricRestriction


How the Aging Immune System Makes Older People Vulnerable to COVID-19 | Lifespan News
Sep 22 2020 7 mins  
Lifespan News is moving to X10's new channel! https://www.youtube.com/lifextenshow ▼▼ Description, sources, and more below ▼▼ In this episode of Lifespan News: 0:00 Intro 0:40 How the Aging Immune System Makes Older People Vulnerable to Covid-19 1:40 A small study on the effects of NMN on COVID-19 2:44 Common diabetes drug reverses inflammation in the liver 4:16 Brown Fat Transplantation Reduces Obesity in Mice 5:52 Tissue Engineering and Regenerative Medicine in Longevity Visit https://youtube.com/BrentNally for more of Brent's content! Executive Producer: Keith Comito Producer: Nicola Bagalà Assistant Producer: Sedeer el-Showk Video Editors: Tim Maupin, Brent Nally Text Editor: Josh Conway SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ How the Aging Immune System Makes Older People Vulnerable to Covid-19: https://www.nytimes.com/2020/09/08/health/covid-aging-immune-system.html https://www.lifespan.io/news/aging-is-the-foremost-risk-factor-for-covid-19-lets-fight-it/ A small study on the effects of NMN on COVID-19: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3677428 On NAD+: https://www.lifespan.io/news/why-nad-declines-during-aging-part-1/ https://www.lifespan.io/news/why-nad-declines-during-aging-part-2/ Common diabetes drug reverses inflammation in the liver: https://www.eurekalert.org/pub_releases/2020-09/si-cdd090920.php Brown Fat Transplantation Reduces Obesity in Mice: https://www.lifespan.io/news/brown-fat-transplantation-reduces-obesity-in-mice/ Tissue Engineering and Regenerative Medicine in Longevity: https://www.lifespan.io/news/tissue-engineering-and-regenerative-medicine-in-longevity/ HOW YOU CAN SUPPORT US ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ If you’d like to help us run this show and/or help Lifespan.io end age-related diseases, you can become a Lifespan Hero: https://lifespan.io/hero. Your support means the world to us! FOLLOW US EVERYWHERE ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Website: https://lifespan.io/lifextenshow Instagram: https://instagram.com/lifespanio Facebook: https://facebok.com/lifespanio Twitter: https://twitter.com/lifespanio Discord: https://discord.gg/HwTX7gR ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ #COVID19 #Aging #ImmuneSystem #NMN #NAD+ #Metformin #Inflammation #CRISPR #obesity #RegenerativeMedicine


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