FERTILITY: Circulating Markers Herald Onset of Preeclampsia


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Jan 08 2007 7 mins   1
Audio Journal of Fertility

Circulating Markers Herald Onset of Preeclampsia
REFERENCE: N Engl J Med 2006; 355:992
RICHARD LEVINE, National Institutes of Health, Bethesda

In pregnant women circulating levels of the anti-angiogenic substances: soluble endoglin and soluble Flt-1 herald the onset of preeclampsia, according to a publication in the New England Journal of Medicine. Richard Levine told Peter Goodwin about his group’s findings from the Calcium for Preeclampsia Prevention Trial which give hope of designing molecularly targeted drugs to treat preeclampsia or of spotting the disease early.