The Ageless Brain Series, Week 3 of 5: Enhancing Neuroprotection


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Mar 12 2025 21 mins  
In this episode of Unreasonable Health, Regan Archibald dives into the fascinating world of nicotine as a nootropic, discussing its cognitive benefits, potential downsides, and how to use it safely. He explores nicotine’s role in dopamine stimulation, memory enhancement, and neuroprotection, even highlighting its potential in preventing neurodegenerative diseases and supporting long-haul COVID recovery. Regan also compares nicotine to peptides like Dihexa and Semax, offering alternatives for brain optimization. The episode challenges long-standing stigmas around nicotine while emphasizing safe sourcing, microdosing, and cycling strategies to avoid dependency. Tune in to discover whether nicotine could be a valuable tool in your cognitive enhancement toolbox.

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