BV #1: Bryan Johnson’s Longevity Diet, How Stress Affects Our Cells, & Whether Glucagon is Evil


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Sep 19 2024 123 mins   53 1 0

Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide



The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/



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Timestamps:


0:00 – intro


0:33 – why we started this podcast


6:25 – our take on Bryan Johnson’s Longevity Blueprint and problems with biohacking


12:13 – whether we should adopt any of the strategies from Bryan Johnson’s Blueprint to achieve optimal health


14:50 – the cost of continually being in a caloric deficit and why this does not increase longevity


21:06 – issues with eating hard-to-digest foods and whether supplements can make up for missing nutrients in the diet


22:13 – the importance of avoiding reductionistic thinking around supplements touted for weight loss benefits


28:00 – potential pros and cons of Bryan Johnson’s Blueprint and how to measure health


32:39 – Bryan Johnson’s supplement protocol


41:09 – how low-carb diets negatively affect NAD+ to NADH ratios and estrogen status


46:20 – whether body fat percentage and cholesterol levels can be too low


52:20 – what is stress?


1:03:20 – issues with hormesis and the idea that stress is beneficial


1:07:34 – whether avoiding stress is possible and how to develop resilience to stress


1:13:17 – addressing Marty Kendall’s response to our take on glucagon and insulin


1:24:17 – glucagon’s short-term and long-term effects on metabolic function


1:26:46 – glucagon’s role in insulin resistance and type 2 diabetes


1:37:16 – metabolic dysfunction as a driver of insulin resistance


1:41:06 – whether we need to be concerned about wasting energy on hormone production


1:44:50 – whether we should always try to avoid gluconeogenesis


1:51:45 – how to use carbohydrates to stabilize your blood sugar


1:56:11 – habit stacking, simplifying supplementation, and adopting a long-term mindset when it comes to health