In this episode of the AI Grand Rounds podcast, Dr. Adam Rodman shares his unique journey from a historian to a physician deeply interested in the intersection of medicine and artificial intelligence. He highlights his unconventional path, driven by an obsession with epistemology and nosology, and his early exposure to AI through historical references and personal experiences with language models. Rodman discusses the evolution of clinical reasoning, the importance of probabilistic models, the implications of AI in diagnostic processes, and details his work with large language models like GPT-4. He also reflects on the balance between the benefits and challenges of AI in medicine, emphasizing the necessity of collaboration between computer scientists and medical professionals. Throughout the episode, Rodman underscores the potential of AI to re-humanize medicine while cautioning against misapplications of the technology.