Nov 21 2024 34 mins 7
As a new microbiologist sometimes terms like beta-lactams, beta-lactamases, or penicillin-binding proteins (PBPs) can be confusing. Are you familiar with the New-Delhi metallo-beta-lactamase (NDM) and its variants? How many are there? How does this enzyme affect beta-lactam drugs?How about NDM-5? In this episode Luis is joined by Dr. Raneem Pallotta, an infectious diseases pharmacist. In the episode we go over these terms. Dr. Pallotta also talks about an NDM-producing E. coli that harbors PBP3 variants. How do these variants affect beta-lactam antibiotics? Tune in for a great episode.
Link to Dr. Pallotta's article: https://www.contagionlive.com/view/ndm-producing-e-coli-harboring-pbp-insert-variants-emerges-as-new-threat
Link to other articles:
https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-017-1012-8
https://pmc.ncbi.nlm.nih.gov/articles/PMC5527577/
https://pubmed.ncbi.nlm.nih.gov/34800710/
https://pubmed.ncbi.nlm.nih.gov/32040179/
https://pubmed.ncbi.nlm.nih.gov/25634992/
https://www.idsociety.org/practice-guideline/amr-guidance/
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