S1Ep3 Biomarkers and CRC


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Mar 14 2024 18 mins  

Welcome to the third episode of Care Partner's Compass: Navigating CRC on biomarkers.

I am joined again by CRC patient advocate and friend Annie Delores, whose information can be found here or through the podcast's website.

In today's episode, we talk about the basics and importance of biomarkers and colorectal cancer.

Full transcription can be found on the website.

Host, producer/editor, and composer: Elsa Lankford
Guest: Annie Delores

And all the thanks and hugs in the world to Kristine. I can never tell you often enough how incredible you are.

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Helpful links related to this episode:

  • (01:30) - Very basics of biomarkers

  • (02:43) - HER2 (ERBB2) mutation

  • (03:12) - Background on CRC

  • (04:09) - Main CRC biomarkers

  • (05:36) - Where to find the biomarkers

  • (06:45) - MSI - Microsatellite Instability

  • (08:09) - BRAF mutation

  • (08:41) - First line clinical trials based on biomarkers

  • (10:09) - KRAS and Stage 4

  • (10:56) - Targeted treatments

  • (12:17) - It can take time to understand biomarkers

  • (14:05) - NGS (Next Generation Sequencing) reports

  • (14:41) - Inherited mutations

  • (15:12) - Biomarker testing as a standard