#18 David Thorstad: Evidence, uncertainty, and existential risk


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Feb 11 2025 98 mins   4

In this episode, we speak with Dr. David Thorstad: Assistant Professor of Philosophy at Vanderbilt University, Senior Research Affiliate at the Global Priorities Institute, and author of the blog, Reflective Altruism. We discuss existential risks–threats that could permanently destroy or drastically curtail humanity’s future–and how we should reason about these risks under significant uncertainty.

(00:00) Our introduction

(09:32) Interview begins

(14:32) The longtermism shift

(23:17) Framework for objections to longtermism

(29:47) Overestimating existential risk: population dynamics

(36:06) Overestimating existential risk: cumulative vs. period risk

(39:44) Overestimating existential risk: ignoring background risk

(42:14) The time of perils hypothesis

(46:11) When and where should philosophers speculate?

(1:09:02) Extraordinary claims require extraordinary evidence

(1:21:44) Regression to the inscrutable and the preface paradox

(1:30:07) The tendency to quantify

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Bio(un)ethical is a bioethics podcast written and edited by Leah Pierson and Sophie Gibert, with production support by Audiolift.co. Our music is written by Nina Khoury and performed by Social Skills. We are supported by a grant from Amplify Creative Grants.