Here we discuss a Dermatology SAQ with a difference. Starting with an image description and differential diagnoses, we enter into DRESS (Drug reaction with eosinophilia and systemic symptoms). How would you differentiate between DRESS and SJS/TENS? How do you assess and manage an entity like this? And what do you do when a patient with a rash deteriorates? For the SAQ with images, go to www.artofemergency.com