137: Karen Humphries twice survived cholangiocarcinoma | bile duct cancer | liver resection | xeloda | chemotherapy


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Feb 25 2025 19 mins  

After a long list of health issues, Karen Humphries was diagnosed with a rare type of bile duct cancer called cholangiocarcinoma. She was initially diagnosed in 2021 with Stage 2B gallbladder cancer, had her gallbladder removed, after which the diagnosis was changed to Stage 4 cholangiocarcinoma. Karen underwent a two-part liver resection and a chemotherapy regimen and went into remission. Two years later, she was again diagnosed with cholangiocarcinoma. Her treatment included biliary stents. Karen knows her cancer is incurable but has survived and leads a happy life.

Karen Humphries’ life has been marred by numerous health-related issues. Because of a rare genetic condition, in 2010, she had to wear a colostomy bag. A decade later, she experienced severe vomiting, pale colored stools, an inability to eat solid foods, pain in her right-side ovaries, among others.

She sought medical attention and got a gallbladder scan. That led to the removal of her gallbladder and a diagnosis of Stage 2B gallbladder cancer. The diagnosis was later revised as cholangiocarcinoma, a rare form of bile duct cancer.

Karen underwent a two-part liver resection, appendix and radical lymph node abstraction, and a six-month chemotherapy regimen with xeloda. She responded well and went into remission.

However, in 2023, after biopsies of her neck and liver, the cholangiocarcinoma returned. Doctors told her that her initial diagnosis of Stage 2B gallbladder cancer was actually Stage 4 cholangiocarinoma all along. Her treatment included biliary stents.

Karen’s cancer has been labeled ‘incurable,’ but she undergoes periodic CT and PET scans, and her condition has stabilized. She maintains an upbeat approach to life and mentors others who have been diagnosed with cholangiocarcinoma and other forms of cancer.