Aug 29 2024 23 mins
Drs Ann H. Partridge and Mina S. Sedrak discuss the relationship between cancer and accelerated aging, including treatments that empower patients to lead longer, healthier lives.
Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/999932. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Age and Cancer Risk https://www.cancer.gov/about-cancer/causes-prevention/risk/age
The Aging-Cancer Cycle: Mechanisms and Opportunities for Intervention https://pubmed.ncbi.nlm.nih.gov/36512079/
Chronic Health Conditions in Adult Survivors of Childhood Cancer https://pubmed.ncbi.nlm.nih.gov/17035650/
Anthracycline-Induced Cardiotoxicity: Causes, Mechanisms, and Prevention https://pubmed.ncbi.nlm.nih.gov/32483740/
Clinical Frailty Scale https://pubmed.ncbi.nlm.nih.gov/32644435/
Accelerated Aging in Older Cancer Survivors https://pubmed.ncbi.nlm.nih.gov/34534355/
Characterization of Cellular Senescence in Doxorubicin-Induced Aging Mice https://pubmed.ncbi.nlm.nih.gov/35398171/
Targeting Senescence Induced by Age or Chemotherapy With a Polyphenol-Rich Natural Extract Improves Longevity and Healthspan in Mice https://pubmed.ncbi.nlm.nih.gov/38951692/
Prevention of Frailty With Fisetin and Exercise (PROFFi) in Breast Cancer Survivors (PROFFi) https://classic.clinicaltrials.gov/ct2/show/NCT06113016
Development and Validation of a Risk Tool for Predicting Severe Toxicity in Older Adults Receiving Chemotherapy for Early-Stage Breast Cancer https://pubmed.ncbi.nlm.nih.gov/33444080/
Calculator: Cancer and Aging Research Group-Breast Cancer (CARG-BC) Score for Older Adults https://www.uptodate.com/contents/calculator-cancer-and-aging-research-group-breast-cancer-carg-bc-score-for-older-adults
Cancer and Aging Research Group https://www.mycarg.org/