Mar 04 2024 35 mins
A new 'Magic Bullet' that few people know about (including your doctor!) ... The importance of Methylene Blue and how it might transform human health particularly in areas of low oxygen delivery (fatigue states, depression and neurological damage).
Check out the original recording with Dr Gonalez-Lima on https://deeprootsathome.com/methylene-blue-memory-mood-parkinsons-adhd/ (see the original on rumble linked from there).
See more info on dosing on that website
See his latest summary paper on MB + photobiomodulation with neuro-inflammation here https://pubmed.ncbi.nlm.nih.gov/36203812/
He can also be found on various podcasts here https://www.ihmc.us/stemtalk/episode-107/
00:00 Oldest known drug used for emergency room cyanide poisoning
02:20 Electron Transport Chain in Mitochondria - how it produces cellular energy - a series of reduction/oxidation (redox) reactions where electrons are released - reduction is loss of hydrogen ions (protons) and gain of electrons
05:20 What gets in the way? Cyanide poisoning and some virus infections like HIV or covid, causing low oxygen delivery and assimilation
07:50 Long history of use as an anti-viral against Ebola/HIV and anti malarial.
08:25 MB structure - electrons held in a ring structure as a chromophore (like coloured foods).
10:20 Absorbs in IR range - molecule structure is auto-oxidant as well as electron cycling
12:00 Hormesis and biphasic response operates in CFS/ME - at low doses it is advantageous at higher doses can be damaging
14:00 Neurological benefits in healthy people at lower doses - slow aging, dementia, Parkinson's, as well as a powerful antidepressant , etc
15:14 MB is off patent so not supported by Big pharma unlike anti-depressant drugs which are less and less effective - 'treatment resistant depression'
17:30 High permeability as it passes the blood brain barrier and can optimise cellular respiration with well people. So enhances metabolic production enabling better healing, memory, aging i,e is a nootropic as well as a drug for acute medicine.
21:00 Also upregulates (increases) gene expression of protein (enzyme) production longer term thus increasing capacity for oxygen metabolism
22:00 CFS/ME is a form of metabolic 'poisoning' driven by emotional stress and toxicity
23:20 Cure for bladder infections - becomes pro-oxidant in oxidative stress especially important with the elderly
26:40 Brain function and neurological issues must be coupled to haemodynamic response between oxygen and nitrous oxide in Complex 4 (cytochrome oxidase) facilitated by MB
29:00 Enhancing mental function including extinguishing trauma memories and MB in memory reconsolidation
30:20 Topical application using photobiomodulation of skin tumours with MB and IR light
32:30 Disclaimer. Always contact your medical provider as there are some contraindications. However be aware most doctors are unaware of MB except in emergency situations. Please refer to Dr Gonzalez-Lima's papers to educate your doctor in low grad applications.
33:50 Sources - please do your own research to find
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