Jun 11 2024 34 mins
Surge Biswas is the cofounder and CEO of Nabla Bio, an AI platform to enable precise drug design and high-throughput measurement of drug properties. They recently raised $26M Series A led by Radical Ventures. He has a PhD in Bioinformatics and Integrative Genomics from Harvard University.
Surge's favorite book: Permutation City (Author: Greg Egan)
(00:01) Introduction
(00:07) Generative AI in Drug Design
(01:19) Traditional vs. AI-driven Drug Discovery
(03:42) Designing Antibodies
(05:06) Therapeutic Antibodies Design Process
(07:39) Data Sets for AI in Drug Discovery
(10:48) High Throughput Measurement in Drug Discovery
(13:14) Setting Up High Throughput Screening Assays
(18:46) Multiplexed Screens in Drug Discovery
(21:55) Protein Characterization Techniques
(24:33) Protein-Protein Interactions
(28:12) AI in Protein Characterization
(30:55) Technological Breakthroughs in AI and Bio
(32:36) Rapid Fire Round
(36:27) Conclusion
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