E48: Why AI Agents Need Better Infrastructure with Vasek Mlejnsky (E2B)


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Feb 26 2025 36 mins  

This week, we sat down with Vasek Mlejnsky, CEO and Co-Founder of E2B. E2B is a platform for developers to run AI agents in the cloud securely.

We dive into the journey of starting a company with your best friend in the Czech Republic, building for AI agents before the hype, and why secure code execution is critical for scaling. Vasek also shares how E2B is becoming the go-to runtime for AI applications, the role of evals in agent development, and the challenges of pricing infrastructure while balancing user growth without hyperscaler-style pricing.


Episode Chapters:

  1. Growing up in Czech - 1:55
  2. Building with your friend - 5:25
  3. Starting a company in the US vs Europe - 7:05
  4. State of AI agents - 11:15
  5. Code execution before E2B - 14:00
  6. E2B use cases - 16:10
  7. Becoming AWS for AI agents - 19:00
  8. Raising switching costs - 21:20
  9. Computer use for agents - 26:48
  10. Multi modal opportunities for agents - 30:26
  11. Quick fire round - 34:45


As always, feel free to contact us at [email protected]. We would love to hear ideas for content, guests, and overall feedback.

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