Jan 14 2025 41 mins 1
Ferritin keeps climbing and you’re getting jumpy? Did you consult Haem and then they were bedside 5 minutes later? Ever had to donate your own blood to test the patient for something? Join Nick, Cale and Bashar as we unpack a very special bonus episode on another deadly TLA, HLH.
TIMESTAMPS
3:24 - History of HLH
5:26 - What is a histiocyte?
7:44 - How do you turn *off* an immune response?
8:52 - HLH - A Definition
10:49 - What are NK cells?
13:03 - Primary HLH - "HLH Disease"
13:34 - Secondary HLH - "HLH Syndrome"
14:46 - Causes of familial HLH
16:34 - Infective causes
18:05 - Malignant causes
20:24 - Clinical presentation and diagnostic criteria
32:47 - H-Score
34:36 - Treatment - Replacing Your Dodgy Off Switch
38:04 - Prognosis
38:55 - Take Home Messages
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au