Aug 07 2023 3 mins 6
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Generic Name
Aspart, Lispro, Glulisine
Trade Name
Novolog, Humalog, Apidra
Indication
hyperglycemia with diabetes type 1 and 2, diabetic ketoacidosis
Action
stimulates uptake of glucose into muscle and fat cells, inhibits production of glucose in the liver,
prevents breakdown of fat and protein
| Route | Onset | Peak | Duration |
| Aspart | 10-20 min | 1-3 hr | 3-5 hr |
| Glulisine | 15 min | 1 hr | 2-4 hr |
| Lispro | 15 min | 1-1.5 hr | 3-4 hr |
Therapeutic Class
antidiabetics, hormones
Pharmacologic Class
pancreatics
Nursing Considerations
• assess for symptoms of hypoglycemia or hyperglycemia
• monitor body weight over time
• may cause decreased inorganic phosphates, potassium, and magnesium
• monitor blood sugars every 6 hours, monitor A1C every 3-6 months
