Featuring articles on a nationwide couple-based genetic screening; adjunctive embolization for subdural hematoma; a late-liver-stage attenuated malaria vaccine; and climate change, floods, and human health; a review article on Candida auris infections; a case report of a girl with abdominal pain; and Perspectives on Medicare’s first round of drug-price negotiation; on invisible deaths; on minding the sentinel; and on Saint Didacus, fetal death, and dual loyalty.