International Journal of Stroke: Podcast Series

Stroke and COVID with Dr James Seigler

Idarucizumab is a monoclonal antibody fragment with high affinity for dabigatran reversing its anticoagulant effects within minutes. Patients with acute ischemic stroke on dabigatran treatment may become eligible for thrombolysis with rt-PA. In patients on dabigatran with intracerebral hemorrhage idarucizumab could prevent lesion growth. Carmen Lahiff-Jenkins, Managing Editor of th

Mobile stroke units, otherwise known as MSUs have recently been introduced in the care of patients suspected of having an acute stroke, leading to shortening in the time to thrombolytics, but how does the clinical effectiveness in terms of functional outcome and survival among patients treated in MSU and/or conventional care compare? Carmen Lahiff-Jenkins; Managing Editor of the In

Anecdotal reports and clinical observations have recently emerged suggesting a relationship between COVID-19 disease and stroke; highlighting the possibility that infected individuals may be more susceptible to cerebrovascular events Carmen Lahiff-Jenkins, Managing Editor of the International Journal of Stroke (IJS) spoke to Kieron South and Craig Smith from the University of Manch

Clinical assessment scores in acute ischemic stroke are only moderately correlated with lesion volume since lesion location is an important confounding factor. Many studies have investigated grey matter indicators of stroke severity but the understanding of white matter tract involvement is limited in the early phase after stroke. Carmen Lahiff-Jenkins, Managing Editor for the Inte

In health research we often hear, and pay lip service to the term ‘patient centred‘. Many of us would probably be hard pressed to devise entirely patient centred studies. "Take Charge’ is an impressive, novel, community-based self-directed rehabilitation intervention that helps a person with stroke to take charge of their own recovery. In a previous randomised controlled tria

Controversy and great interest exists regarding cardiovascular and cerebrovascular risk and it’s relationship to sleep duration. Carmen Lahiff-Jenkins, Managing Editor of the International Journal of Stroke spoke to Dr Jingwei Li from the George Institute for Global Health about the paper ‘Secondary analyses of the international, multicenter, Sleep Apnea Cardiovascular Endpoint

The thrombolysis in cerebral infarction scale otherwise known as the (TICI) scale is an important outcome measure to evaluate the quality of endovascular stroke therapy. The TICI scale is ordinal and observer dependent, so this means it may not result in the best prediction of patient outcome and can also provide an inconsistent reperfusion grading. Carmen Lahiff Jenkins Managing E

Coronavirus disease 2019 (COVID-19) is an ongoing pandemic characterized by high morbidity and mortality. Clinical factors that can identify patients at risk for worse outcomes can help in developing risk stratification models for judicious use of healthcare resources. A team of researchers from Italy and the USA performed a pooled analysis of published studies, for assessing the i

On March 11th, 2020 the World Health Organization declared the COVID-19 infection a pandemic. We are currently in the throws of that global infection and the big question everyone is racing to ask and answer is the risk of ischemic stroke higher in patients with COVID-19 infection. We spoke to both Drs based in the United States Adnan Quereshi from the University of Missouri, Depar