ID:IOTS - Infectious Disease Insight Of Two Specialists

One PK table to rule them allOne table to find themOne table to bring them all And in the darkness blind them… …with awesome antibiotic PK facts you can use to bedazzle your friends and enemies alike! Prep notes here. Support the showQuestions, comments, suggestions to [email protected] or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not

The last Pharmacokinetics episode had finally been …Excreted! This episode covers the ‘drug out’ bit of pharmacokinetics, including things such as: -What is clearance? -how to calculate half life and -doesn’t everything leave through the kidneys anyway? (That is sort of true, also shut up). Check out our prep notes (including for this episode) here. Support the showQues

It's the second Pharmacokinetics episode you never knew you wanted! Let’s talk about how antibiotics are distributed around the body once absorbed, using the examples of Amoxicillin and CallumShutUpicillin (listen to episode for clarification).What exactly is the volume of distribution? Want a handy reference for the plasma protein binding of various antimicrobials? Then thi

It's the Pharmacokinetics episode you never knew you wanted! Callum didn't know either, but never mind that let's talk about how antibiotics are absorbed, and how we can use that to improve our use of them in clinical practice. Want ammunition for that oral switch? Got someone who's doubting oral antibiotics' effectiveness? Then this is the episode for you!

In this final episode of the Nobbling the Nonfermentors mini-series, Jame and Callum discuss the (mostly historical) pathogen Burkholderia mallei, causative agent of Glanders. We did it. We got to the end. Nonfermentors... Nobbled. Support the showQuestions, comments, suggestions to [email protected] or on X/Threads @IDiots_podPrep notes for completed episodes can be foun

Post-publication, Callum and Jame give a little extra information on the SABATO trial in its final form compared to it's pre-publication state. Final article here:Efficacy and safety of an early oral switch in low-risk Staphylococcus aureus bloodstream infection (SABATO): an international, open-label, parallel-group, randomised, controlled, non-inferiority trial, Kaasch, Achim

JOURNAL CLUB, YO, IT’S A SABATO!!!Join Jame and Callum as we travel back in time to when we recorded this deep dive into the SABATO trial pre-print, now peer-reviewed and published in the Lancet ID!In the next episode we'll give a little update as to how the final article differs from the preprint (not much). We also talked about in our FIS Highlights Episode 3. We loved thi

In this penultimate episode in the Nobbling the Nonfermentors mini-series, Jame and Callum discuss the regionally important neglected tropical disease Melioidosis, caused by Burkholderia pseudomallei.This episode was based disproportionately on the following article, and we extend our thanks to the authors for thoughfully publishing it so close to us wanting to do a podcast episode

In this Episode, Callum reflect on his recent runaway success passing the FRCPath Part 2, passes on some tips and tricks for the exam, and then we talk about what 3 antibiotics we would take with us to a Desert Island (that has all pathogens and environments where you would find said pathogens, so not just a desert apparently). 'Prepping to Pass' episodes mentioned: 40, 4

How do you think about antibiotics?This Christmas we give the best gift of all: no puns in an episode.Join Jame and Callum as they talk about a method for thinking about and explaining antibiotics.Here are the show notes for this episode: https://idiots.notion.site/69-Choosing-an-antimicrobial-4e7446a91ff6413aa14924a2ba905ffa Support the showQuestions, comments, suggestions to idi