Everything Epigenetics

Feb 07 2024 9
Everything Epigenetics Podcast artwork

Don’t understand epigenetics? Don’t worry. There was a time when genetic analysis was hardly known or understood. Now, genetic analysis is performed by thousands of companies and your full genome can be decoded for less than $100. Epigenetics is how your behaviors change your outcome .Epigenetics gives us knowledge on how to change your life, and the ability to read biology to understand your current health status. You ARE in control. Your host, Hannah Went, is here to discuss the insights which can improve your life and health. She is here to bring you Everything Epigenetics, simplified. 

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Epigenetic Gestational Age Prediction with Kristine Løkås Haftorn

Feb 07 2024 56 mins  
Determining a newborn's due date traditionally relies on maternal reports of the last menstrual period and ultrasound scans. These conventional approaches can lead to uncertainties, especially when it comes to identifying deviations from normal fetal development that could impact research into the effects of preterm or post-term births on newborns.However, researchers, includi

Causal Epigenetic Age Uncouples Damage and Adaptation with Kejun (Albert) Ying

Jan 24 2024 46 mins  
Machine learning models that use DNA markers can estimate the age of biological samples. However, understanding why these markers change with age is challenging because it's hard to prove that these changes cause aging-related traits. In this week’s Everything Epigenetics podcast, I speak with Kejun Ying who uses large datasets to find specific DNA markers that directly infl

The Importance of the Imprintome with Dr. Randy Jirtle

Jan 10 2024 54 mins  
The idea of the impintome is still foreign to many people. So, let’s start with a simple explanation.For the majority of genes, we inherit two functional copies—one from our mother and one from our father. However, imprinted genes follow a different pattern, as we inherit only one functional copy. Depending on the specific gene, either the copy from our mother or our father und

Integrating Epigenetics into the Social Models of Heath Disparities with Dr. Lauren Schmitz

Dec 27 2023 52 mins  
Did you know that the Great Depression—the worst economic downturn in US history—impacted how fast individuals aged biologically decades later according to their epigenetic aging profiles?!Yep… you read that right. Results show that faster epigenetic aging later in life is associated with worse economic conditions, specifically, during the prenatal period, suggesting it may b

Prioritizing Your Health Investment with Dr. Jeoff Drobot

Dec 13 2023 54 mins  
I always have a great time chatting with Dr. Jeoff Drobot, and in this podcast he doesn’t disappoint. He is an expert in “age accounting” and often speaks about biological age in terms of environmental debits and credits..What does this look like? Well, retirement should not be the first time you start thinking about longevity. Just like a small amount of money invested well

Unlocking the Epigenome from a Single Drop of Blood with Dr. Toinét Cronjé

Nov 29 2023 49 mins  
In this week’s Everything Epigenetics episode, I speak with Dr. Toinét Cronjé about what epigenetics can do for the field of epidemiology. Epidemiology is the study of the distribution and determinants of health-related states or events in populations and the application of this study to control health problems. By studying epigenetics and epidemiology in tandem, Dr. Cronjé se

Tracking and Measuring Biomarkers to Maximize Longevity with Dr. Michael Lustgarten

Nov 15 2023 63 mins  
In this week's Everything Epigenetics episode, I speak with Michael Lustgarten on tracking and measuring biomarkers to maximize longevity. His long-standing goal is to live longer than everyone that has ever lived. To do that, he plans on using the best available science to “biohack” his way to super-longevity. Contrary to the prevailing belief that aging is an inescapable

Methylation Risk Scores with Dr. Mike Thompson

Nov 01 2023 62 mins  
You may be familiar with polygenic risk scores (PRS), but have you ever heard of methylation risk scores (MRS)? MRS are crucial to understand, as they’re a tool that quantifies DNA methylation levels at specific genomic regions linked to particular conditions, shedding light on the potential impact of epigenetic modifications on disease susceptibility.In contrast, PRS calculates

The Role of Epigenetics in Functional Medicine with Dr. Jeffrey Bland

Sep 27 2023 56 mins  
In this Everything Epigenetics episode, Dr. Jeffrey Bland and I discuss his significant contributions to functional medicines and how he has shaped this field. We also define functional medicine as a multidisciplinary approach that draws on the expertise of various healthcare professionals, including doctors, nutritionists, and researchers, to address complex health issues from a h

Assessing the Reproducibility and Integrity of DNA Methylation with Dr. Karen Sugden

Sep 13 2023 58 mins  
The reliability of testing epigenetic DNA methylation using Illumina beadchips is of paramount importance due to the specific intricacies of this technology. Illumina beadchips are widely used platforms for high-throughput epigenetic analysis, employing thousands of probes to measure DNA methylation levels at specific genomic loci. In this week’s Everything Epigenetics podcast, D