AI + a16z

Jan 10 2025 32 ep. 40 mins 103
AI + a16z Podcast artwork

Artificial intelligence is changing everything from art to enterprise IT, and a16z is watching all of it with a close eye. This podcast features discussions with leading AI engineers, founders, and experts, as well as our general partners, about where the technology and industry are heading.

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From NLP to LLMs: The Quest for a Reliable Chatbot

Jan 10 2025 38 mins  
a16z General Partner Martin Casado and Rasa cofounder and CEO Alan Nichol discuss the past, present, and future of AI agents and chatbots.

Best of the Year: Building AI Companies

Dec 27 2024 46 mins  
A 2024 highlight reel, featuring founders sharing their insights, advice, and experiences building AI companies — from foundation-model labs to vertical applications.

Can AI Agents Finally Fix Customer Support?

Dec 18 2024 44 mins  
Decagon CEO Jesse Zhang and a16z partner Kimberly Tan discuss how LLMs are reshaping customer support, the strong market demand for AI agents, and how AI agents give startups a a new pricing model to help disrupt incumbents.

REPLAY: Scoping the Enterprise LLM Market

Nov 30 2024 43 mins  
This is a replay of our first episode from April 12, featuring Databricks VP of AI Naveen Rao and a16z partner Matt Bornstein discussing enterprise LLM adoption, hardware platforms, and what it means for AI to be mainstream.

Building Developers Tools, From Docker to Diffusion Models

Nov 15 2024 41 mins  
Replicate cofounder and CEO Ben Firshman, and a16z partner Matt Bornstein, discuss the art of building products and companies that appeal to software developers. Ben was the creator of Docker Compose, and Replicate has a thriving community of developers hosting and fine-tuning their own models to power AI-based applications.

The Best Way to Achieve AGI Is to Invent It

Nov 04 2024 38 mins  
Longtime machine-learning researcher Pedro Domingos joins a16z General Partner Martin Casado to discuss the state of artificial intelligence, whether we're really on a path toward AGI, and the value of expressing unpopular opinions.

Neural Nets and Nobel Prizes: AI's 40-Year Journey from the Lab to Ubiquity

Oct 25 2024 40 mins  
a16z General Partner Anjney Midha shares his perspective on the recent collection of Nobel Prizes awarded to AI researchers in both Physics and Chemistry. He talks through how early work on neural networks in the 1980s spurred continuous advancement in the field — even through the "AI winter" — which resulted in today's extremely useful AI technologies.

How GPU Access Helps AI Startups Be Agile

Oct 23 2024 39 mins  
GPU access is like oxygen to AI startups: without it, they can't breathe. Here, a16z General Partner Anjney Midha explains the forces that lead to GPU shortages and price spikes, and how the firm mitigates these concerns for portfolio companies.

DisTrO and the Quest for Community-Trained AI Models

Sep 27 2024 72 mins  
Bowen Peng and Jeffrey Quesnelle of Nous Research join a16z General Partner Anjney Midha to discuss their mission to keep open source AI research alive and activate the community of independent builders. The focus is on a recent project called DisTrO, which demonstrates it's possible to train AI models across the public internet much faster than previously thought possible.

Balancing AI Expertise and Industry Acumen in Vertical Applications

Sep 13 2024 42 mins  
Ambience cofounder and chief scientist Nikhil Buduma discusses the nuances of using AI models to build vertical applications (including in his space, health care), and why industry acumen is at least as important as technical expertise.