JAMA Medical News

Apr 04 2025 235 ep. 20 mins 3.7k
JAMA Medical News Podcast artwork

Discussions of timely topics in clinical medicine, biomedical research, public health, health policy, and more, featured in the Medical News section of JAMA, the Journal of the American Medical Association.

  Health & Fitness  Science
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Can Open-Source LLMs Compete With Proprietary Ones for Complex Diagnoses?

Apr 04 2025 18 mins  
A recent study published in JAMA Health Forum suggests that institutions may be able to deploy custom open-source large language models (LLMs) that run locally without sacrificing data privacy or flexibility. Coauthors Thomas A. Buckley, BS, and Arjun K. Manrai, PhD, from the Department of Biomedical Informatics at Harvard Medical School join JAMA+ AI Editor in Chief Roy H. Perlis,

March 2025 Medical News Summary

Mar 28 2025 20 mins  
The US Is Suing Pharmacies for Aiding in the Opioid Crisis; Texas Measles Outbreak Spurs Call for Stronger Vaccine Advocacy; Study Finds Sleep-Related Infant Deaths Are on the Rise Related Content: US Government Sues Pharmacy Chains CVS and Walgreens for Their Alleged Role in the Opioid Epidemic Amid Texas Measles Outbreak, Clinicians Struggle to Offset Increasing Vaccine Hesitan

Rethinking Race in Prenatal Screening for Open Neural Tube Defects

Mar 28 2025 15 mins  
Correction: This podcast has been updated to add additional context on the frequency of false positives. Open neural tube defects affect approximately 1 in 1400 births. Daniel Herman, MD, PhD, of the University of Pennsylvania Perelman School of Medicine joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss a quality improvement study examining the need to continue to

AI’s Role in Advancing Equity for Individuals With Developmental Disabilities

Mar 21 2025 14 mins  
Artificial intelligence (AI) in health care is advancing, despite concerns about how its use may impact health disparities. Dimitri Christakis, MD, MPH, chief health officer at Special Olympics, joins JAMA Associate Editor Yulin Hswen, ScD, MPH, to discuss AI’s potential role in improving health care delivery for people with intellectual and developmental disabilities. Related C

Prescreening for Clinical Trial Eligibility Using Large Language Models

Mar 14 2025 12 mins  
A recent study showed AI-assisted screening using a large language model tool reduced time to determine trial eligibility compared with manual methods. Author Alexander J. Blood, MD, MSc, cardiologist at Brigham and Women's Hospital, and Associate Director of the Accelerator for Clinical Transformation Research Group at Harvard Medical School joins JAMA Associate Editor Yulin Hswen

Machine Learning for Earlier Diagnosis of Schizophrenia

Mar 07 2025 16 mins  
In a recent study published in JAMA Psychiatry, researchers reported that a machine learning model was able to stratify risk for subsequent diagnosis of schizophrenia or bipolar disorder among individuals already receiving psychiatric treatment. Coauthor Søren Dinesen Østergaard, PhD, of Aarhus University in Denmark joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discus

The 5 Ways Engineers Plan to Curb Antimicrobial Resistance

Feb 28 2025 18 mins  
A recent report from the Engineering Research Visioning Alliance emphasizes the urgent need for engineering-directed research to mitigate the growing threat of antimicrobial resistance. Anita Shukla, PhD, a professor of engineering at Brown University, discusses its findings with JAMA Medical News Associate Managing Editor Kate Schweitzer and presents several key opportunities. Re

February 2025 Medical News Summary

Feb 28 2025 11 mins  
Changes to CDC’s Website Threaten Patients, Public Health; Landmark Study of Black Women and Cancer Launches Related Content: As Missing and Altered CDC Webpages Threaten Patient Care, Efforts Grow to Fill Information Gaps Landmark Study Aims to Enroll 100 000 Black Women to Investigate Their Cancer Risks and Outcomes

Language Equity in Health Technology

Feb 28 2025 19 mins  
AI can play a role in addressing language barriers in health care. In a recent Editorial in JAMA Network Open, Pilar Ortega, MD, MGM, of the University of Illinois College of Medicine, and coauthors emphasized the urgent need for integrating language equity into digital health solutions. Dr Ortega joins JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, to discuss. Related

AI Guided Diagnostic-Quality Lung Ultrasound

Feb 21 2025 11 mins  
Lung ultrasound aids in the diagnosis of patients with dyspnea but requires technical proficiency for image acquisition. Cristiana Baloescu, MD, MPH, of Yale School of Medicine, joins JAMA Associate Editor Yulin Hswen, ScD, MPH, to discuss a new study published in JAMA Cardiology evaluating the ability of AI to guide acquisition of diagnostic-quality lung ultrasound images by train