Night Science

Dec 16 2024 68 ep. 37 mins 270

Night Science Podcast artwork

Where do ideas come from? In each episode, scientists Itai Yanai and Martin Lercher explore science's creative side with a leading colleague. New episodes come out every second Monday.

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67 | A hypothesis is a liability

Dec 16 2024 39 mins

In this episode, Itai and Martin delve into the interplay between hypothesis-driven and exploratory research, drawing on insights from past guests of the Night Science Podcast. They discuss how being focused on a single hypothesis can prevent us from making discoveries, while emphasizing the value of open-ended exploratory analyses—often dismissed as “fishing expeditions.” Th

66 | Michael Fischbach and the scientific decision tree

Nov 25 2024 50 mins

In this episode, Stanford professor Michael Fischbach discusses insights from his course on how to choose meaningful research problems. Highlights include:- Invest time in problem selection: Spend more time upfront selecting the right research problem.- Date ideas: Before settling on an idea, explore multiple alternatives without emotional attachment.- Fixed vs. floating parameters

65 | James Kaufman and the art of creativity maintenance

Nov 04 2024 30 mins

James Kaufman, Professor of Educational Psychology at the University of Connecticut, discusses the psychological underpinnings of creative thinking with Itai & Martin. Together, we delve into the complex nature of creativity, exploring its roots as both a trait and a skill that can be nurtured. We examine the role of personality traits in creativity, the impact of interdiscipli

64 | Robert Weinberg and the perils of being a Fachidiot

Sep 30 2024 42 mins

MIT's Bob Weinberg is perhaps the world's most prominent cancer researcher. In this episode, Bob emphasizes that true innovation often comes from blending ideas from different fields – a synthesis that transcends the boundaries of one's primary area of research. We discuss the vital role of human interaction, with many scientific breakthroughs coming from informal collaborations

63 | Manu Prakash and how the discovery changes you

Sep 09 2024 44 mins

Manu Prakash is a professor of bioengineering at Stanford University, asking biological questions with insights from physics. His most widely known contribution is the FoldScope, a $1-microscope made from paper and a lens – 2 million copies of this have been distributed to would-be scientists around the world. In this episode, Manu emphasizes how science is a sense of wonder and

62 | Dianne Newman and the visceral and intentional sides of science

Aug 19 2024 40 mins

Dianne Newman – a molecular microbiologist at CalTech – is a professor both in Biology and Geology. In this episode, she encourages young scientists to pursue questions to which they have a visceral connection, rather than following popular trends. In its search for fundamental truths guided by our inner biases and preferences, Dianne likens scientific curiosity to artistic exp

61 | Tina Seelig on what to do with a really bad idea

Jul 15 2024 29 mins

Tina Seelig is Executive Director of the Knight-Hennessy-Scholars at Stanford University. She is widely known for teaching creativity courses and workshops with an entrepreneurial focus. In this episode, Tina emphasizes the importance of living in the problem space longer, taking time to challenge assumptions and reframe questions before rushing to solutions. We discuss how deliber

60 | Venki Ramakrishnan and the secrets of doing science over tea

Jul 01 2024 33 mins

Venki Ramakrishnan shared the 2009 Nobel Prize in Chemistry for uncovering the structure of the ribosome. He runs a lab at the MRC Laboratory of Molecular Biology in Cambridge, England. In this episode, Venki emphasizes the importance of enjoying the scientific process itself, not just aiming for major discoveries. He describes his creativity as a result of mulling over a problem a

59 | Jennifer Oyler-Yaniv and the point of creative frustration

May 27 2024 36 mins

Jennifer Oyler-Yaniv is a professor working on the immune system at Harvard’s Medical School. In this episode, we discuss with her how she teaches creativity in her course for PhD students. We explore the emotional roller coaster ride of research projects, typically culminating in the point of creative frustration, where we get stuck and are tempted to either give up or take an e

58 | Guy Yanai on Pentimenti

May 14 2024 24 mins

Guy Yanai is a painter whose work is displayed in many public and private collections across the US, Europe, and Asia, including, for example, the Tel Aviv Museum of Art. His distinctive painting style blends modernist, abstract tendencies together with references to everyday life and popular culture. Coincidentally, Guy is also Itai’s brother. Together, we explore the many simil