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In today’s episode, we’re expanding on last week’s biohacking mindset chat and taking a closer look at extra prescription medications for weight management. (If you missed it, give it a listen now for the full context!) We’ll discuss how these options might fit into your current plan, why you might consider adding them, and how tailoring your approach can really make a difference.

Join me as I break down how medications like Contrave, Qsymia, and metformin can fit into a personalized approach to weight management. Remember, this episode aims to provide information to help you better understand your options and have more informed conversations with your healthcare provider—it is NOT personalized medical advice. Tune in now to explore more avenues on your weight management journey!

References

Last week’s episode (Ep. 105): Optimizing Your Toolbox: Biohacking with Anti-Obesity Meds

To learn more about specific weight loss percentages, check out this episode here: Anti-Obesity Medications: Part 2

Audio Stamps

00:30 - A quick reminder to listen to Part 1, Optimizing Your Toolbox: Biohacking with Anti-Obesity Meds, before diving into this episode.

01:00 - Dr. Rentea shares some updates, including an upcoming YouTube channel and a paid podcast launching in March with exclusive content and community access.

05:33 - Today's episode explores alternative medications that can help if GLP-1s aren’t an option or aren’t working as expected.

09:02 - Qsymia (Phentermine + Topamax) can help with hunger, but side effects make it hard for most to tolerate.

11:20 - Contrave can help with intense cravings and snacking when dietary changes aren’t enough.

13:20 - Orlistat causes minimal weight loss with unpleasant side effects and is rarely prescribed or covered.

14:48 - Metformin aids insulin resistance and supports weight loss without causing low blood sugar.

16:35 - There are more weight loss options beyond GLP-1s, and your provider should be able to explain why certain medications may or may not be right for you.

Quotes

“Always know, if one thing doesn't work, there is always more that can be done if you're really seeing a skilled weight management expert.”

“Everyone’s physiology is different. We're talking about how to make your physiology work for you.”

“If someone is a hyporesponder and they continue to struggle despite dietary changes and exercise and all the things we're doing, I do find that for some people metformin can be that magic continuation that they need.”

“If you have significant insulin resistance, which is usually the case when you have a really hard time releasing weight, I find that metformin can be incredibly helpful as an add on.”

“Remember the name of the game is weight stability so that you don't have this metabolic up and down.”

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