Autism – ASF Weekly Science Podcasts

Nov 25 2024 50 ep. 14 mins 5

Autism – ASF Weekly Science Podcasts artwork

The Autism Science Foundation Weekly Science Podcast is a summary of the latest research in autism spectrum disorders. This podcast will discuss new science, research discoveries, meetings and discussions, news reports, and other information important to those affected by autism especially families.

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Synaptic Density and Autism, explained

Nov 25 2024 12 mins

….or at a podcast with at least an attempt at an explanation of what synaptic density is and how it is affected in brains of people with autism. This week we review three convergent lines of evidence – whole brain, brain cell then genes within those brain cells – that show that the autistic brain has a decrease in cell-to-cell communication in multiple brain regi

Where is autism stigma the worst in the world?

Oct 20 2024 17 mins

This week, part 1 in cultural stigma around autism with Mia Kotikovski provides an overview of stigma, where it can come from across cultures and provides some examples of stigma in different countries. Different areas of the world are in different places in terms of their perceptions of autism, their needs for autism families, and what they perceive as their greatest difficulties

Mysteries of the Microbiome

In the first of a two-part series on digestive health in ASD, Mia Kotikovski summarizes scientific information about what the complicated microbiome is, how it influences physical and psychiatric health, if it is altered in autism, and what causes it to be different in ASD. * https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638778/ * https://www.frontiersin.org/journals/cellul

More about the environmental influences in autism

Sep 08 2024 15 mins

New research points to a previously understudied but fascinating mechanism by which environmental factors may lead to autism: it’s called the “GABA/glutamate switch” which is a critical period in development when certain cells turn from turning on cell activity to turning them off. These environmental factors may delay this process leading to long term effects on

Research for the end of Autism Action Month

Apr 28 2024 14 mins

In honor of the last week of Autism Awareness/Acceptance Month, we review two new scientific findings that call for more awareness and action, and less acceptance of the status quo. First: sex differences in autism are not well understood, and as it turns out, the influences on a diagnosis are different. Males have a higher rate of heritability compared to females. Second, those w

How to predict severe and dangerous behavior

Jan 07 2024 14 mins

On the first podcast of 2024, we describe a new paper in the Journal of the American Medical Association or JAMA which uses physiological measurements like heart rate and skin conductance to predict severe and dangerous behaviors, specifically aggression. If aggression can be predicted, it might be able to be prevented. It turns out aggression can be predicted up to 3 minutes befo

What’s the latest on minocycline for autism?

Dec 17 2023 12 mins

This week’s podcast re-explores a question about a potential therapy for autism – minocycline. Minocycline is an antibiotic used to treat a number of different infections and some anecdotal reports have linked it to an improvement of autism. This has led to some experimental trials on minocycline, with inconclusive results. This week, a multisite study showed NO effect

Nobody ever talks about catatonia

Nov 05 2023 24 mins

Nobody ever talks about catatonia in autism. This podcast explores the symptoms of catatonia, how to measure it, what parents should know about tracking the symptoms, what the treatments are, and what the causes are. Dr. Martine Lamy from Cincinnati Children’s Hospital explains her work looking at genetic causes in those with catatonia and neurodevelopmental disorders. It

Little Brains Answer Big Questions

Oct 14 2023 34 mins

This week we talk to Sergiu Pasca from Stanford University. He has revolutionized the field of understanding the field of brain development in neurodevelopmental disorders and just published a new study which examined the genetic influence of brain assembly. The way he does this is quite remarkable. His lab uses assembloids, which are many many many stem cells which form into a ti

Now you know the reason for decades of eye tracking research

Sep 10 2023 22 mins

Can biomarkers that measure things like visual social attention be a good proxy for an in person behavioral diagnosis? Why would this be important? This week’s podcast explores two new studies the the Journal of the American Medical Association that show a simple device called EarliPoint can be used to shorten the wait times to receive a diagnostic evaluation. Currently auti