The Stem Cell Podcast

Apr 01 2025 10 ep. 86 mins 3.2k
The Stem Cell Podcast artwork

Join Drs. Daylon James and Arun Sharma as they discuss the latest stem cell research, and interview some of the brightest minds in the field. Brought to you by STEMCELL Technologies.

  Science
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Ep. 291: “Functional Precision Medicine” Featuring Dr. Scott Younger

Apr 01 2025 85 mins  
Dr. Scott Younger is the Director of Disease Gene Engineering within the Genomic Medicine Center at Children's Mercy Hospital. His research focuses on producing patient-derived cellular models to develop functional precision medicine. He talks about using personalized antisense oligonucleotides to reverse disease phenotypes in organoid models of Duchenne muscular dystrophy. He also

Ep. 290: “ISSCR 2025: Illuminating the Future” Featuring Drs. Valentina Greco, Kathryn Cheah, and Eugenia Piddini

Mar 18 2025 82 mins  
Dr. Valentina Greco is the President of the International Society for Stem Cell Research (ISSCR), and Professor of Genetics and Co-Chair of the Status of Women in Medicine at Yale University. Dr. Kathryn Cheah is an ISSCR Program Committee Co-Chair and Emeritus Professor and Chair of Biochemistry at Hong Kong University. Dr. Eugenia Piddini is also an ISSCR Program Committee Co-Cha

Ep. 289: “Heart-Forming Organoids” Featuring Dr. Robert Zweigerdt

Mar 04 2025 86 mins  
Dr. Robert Zweigerdt is a Principal Investigator at Hannover Medical School, where his lab focuses on cardiac differentiation and the scalable culture of PSCs. He talks about regulating the lineage-specific differentiation of hPSCs and generating heart-forming organoids that mirror developmental cardiogenesis. He also discusses the importance of mentorship and the benefits of an in

Ep. 288: “Cerebellar Organoids” Featuring Dr. Giorgia Quadrato

Feb 18 2025 82 mins  
Dr. Giorgia Quadrato is Assistant Professor of Stem Cell and Regenerative Medicine at the University of Southern California. Her research focuses on brain developmental and neural organoids. She talks about protocols for generating cerebellar organoids, including those with functional Purkinje cells. She also discusses a transcriptomic atlas of neural organoids and the stem cell re

Ep. 287: “Blood Development” Featuring Drs. Andrew Elefanty and Elizabeth Ng

Feb 04 2025 89 mins  
Drs. Andrew Elefanty and Elizabeth Ng are Senior Principal Investigator and Principal Investigator, respectively, at the Murdoch Children's Research Institute. In the Blood Development group, they aim to develop innovative cellular therapies for blood and cartilage-related diseases. They talk about their recent study deriving and transplanting HSCs, their work on reporter lines, an

Ep. 286: “Neural Lineage Identity” Featuring Dr. Marius Wernig

Jan 21 2025 84 mins  
Dr. Marius Wernig is a Professor of Pathology and a Co-Director of the Institute for Stem Cell Biology and Regenerative Medicine at Stanford University, where his research interests include direct reprogramming and neurological disease modeling. He talks about his early work reprogramming neuronal cells from fibroblasts, adopting iPSCs, and growing his lab. He also discusses his re

Ep. 285: “Funding the Future” Featuring Dr. Jonathan Thomas

Jan 07 2025 91 mins  
Guest: Dr. Jonathan Thomas "JT" is the President and CEO of the California Institute for Regenerative Medicine (CIRM), an organization that provides funding for stem cell research with the purpose of accelerating treatments for patients in need. He talks about working to ensure diversity in clinical trials and developing treatments that are affordable and accessible to patients. He

Ep. 284: “Organ Chip Engineering” Featuring Dr. Milica Radisic

Dec 10 2024 82 mins  
Dr. Milica Radisic is a Professor and Canada Research Chair at the University of Toronto. Her lab uses organ-on-a-chip engineering to mimic physiology of the heart, kidney, and vasculature for the purpose of modeling human disease and discovering more effective drugs. In this episode, she talks about the challenges of studying the heart and strategies to mature cardiomyocytes. She

Ep. 283: “Molecular Hematopoiesis” Featuring Dr. Cynthia Dunbar

Dec 03 2024 90 mins  
Dr. Cynthia "Cindy" Dunbar is National Institutes of Health (NIH) Distinguished Investigator and Chief of the Translational Stem Cell Biology Branch at the National Heart, Lung, and Blood Institute of the NIH. She talks about using macaques to study hematopoiesis and aging, and the challenges and considerations for using these models. She also discusses her collaborative study tran

Ep. 282: “Whole-Body Regeneration” Featuring Dr. Mansi Srivastava

Nov 26 2024 94 mins  
Dr. Mansi Srivastava is Professor of Organismic and Evolutionary Biology at Harvard University and Curator of Invertebrate Zoology at the Harvard Museum of Comparative Zoology. Her lab uses distantly related species to study evolution and regeneration. She talks about establishing Hofstenia miamia, or the three-banded panther worm, as a model system. She also discusses her lab's wo