Axial Podcast

Apr 11 2024 38 ep. 57 mins 11
Axial Podcast artwork

Conversations with great founders and inventors in life sciences. Axial partners with great founders and inventors. We invest in early-stage life sciences companies such as Appia Bio and Seranova Bio often when they are no more than an idea. If you or someone you know has a great idea or company in life sciences, Axial would be excited to get to know you and possibly invest in your vision and company. We are excited to be in business with you - email us at   [email protected] Read our newsletter: https://axial.substack.com/

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Directed Evolution of Antibodies with Doug Chapnick

Apr 11 2024 54 mins  
Doug Chapnick is the Co-Founder and CEO of BioLoomics. A platform company using directed evolution to discover antibody therapeutics. Combining cell line engineering, machine learning, and imaging. At the core of BioLoomics' technology is directed evolution, a process that mimics natural evolution in the lab. The company uses this to create biologics for a given property like t

Building the Ultimate Patent Assistant with Evan Zimmerman

Apr 10 2024 60 mins  
Evan Zimmerman is the Co-Founder and CEO of Edge, that helps patent attorneys, patent agents, and inventors make the patent process less painful and more effective. He earned a Juris Doctor (JD) degree from the UC Berkeley Law School, where he specialized in IP law. Seeing the potential of AI to transform the patent system, Zimmerman teamed up with Len Boyette, an early employee at

Improving Software Engineering in Biostatistics with Daniel Sabanés Bové

Apr 10 2024 53 mins  
Daniel Sabanés Bové⁠ is a senior principal data scientist at Roche. In our conversation, we discuss the need for better software in biotech and his career in data science. Daniel studied statistics at Ludwig Maximilian University of Munich in Germany, earning his PhD in 2013 from the University of Zurich in Switzerland. His doctoral research focused on Bayesian model selection.

Transforming biomanufacturing using software with Martin Permin

Mar 03 2024 51 mins  
Excited to have a conversation with Martin Permin, Founder and CEO of Invert. The company is on a mission to transform biomanufacturing through advanced software and data analytics. We discuss the founding of Invert, what capabilities they give their customers, and the importance of biomanufacturing to grow biological products like proteins, enzymes, and specialty chemicals. Produc

Let the Best Drug Win with Errik Anderson

Jan 04 2024 57 mins  
Errik Anderson is the CEO and Founder of ⁠⁠Alloy Therapeutics⁠⁠. Founded in 2017, the company democratizes access to drug discovery platforms and services. In our conversation, we discuss Alloy's product offering and story. Alloy has rapidly grown into a thriving ecosystem empowering the global scientific community. The company's innovative business model is centere

Leadership and Bioengineering with Omar Ali

Jul 08 2023 80 mins  
Omar Ali is the Senior Director of Research at Lyell Immunopharma. Omar discusses leadership lessons he's picked up across 2 decades working at the intersection of bioengineering and drug development. Starting his first company during grad school at Harvard. Afterwards spending ~7 years at the Wyss Institute for Biologically Inspired Engineering. Setting up his second startup,

Synthetic Biology and Rapid Evolution with Chang Liu

Jul 08 2023 60 mins  
Chang Liu is a professor at UC Irvine pioneering the application of rapid evolution in synthetic biology and protein engineering. We discuss his career and what it takes to startup & lead a new academic lab. Chang's work spans the fields of genetic engineering, synthetic biology, chemical biology, cell biology, and directed evolution. Where his lab engineers specialized gen

Founding Unlearn and Revolutionizing Clinical Trials with Charles Fisher

Jul 08 2023 64 mins  
Charles Fisher is the Founder and CEO of Unlearn, that creates digital twins with AI to enable more efficient clinical trials. Founded in 2017, Unlearn started as a generative AI company looking for a problem, ending up on clinical trials & transforming how they are run. A digital Twin is a longitudinal/clinical record using baseline data from a patient before they receive thei

Imaging Dyes and Microscopy with Luke Lavis

Jul 08 2023 86 mins  
Luke Lavis is a senior group leader and head of molecular tools and imaging at HHMI’s Janelia Research Campus. Luke Lavis works at the interface of chemistry and biology, developing small-molecule fluorescent dyes to illuminate biological samples. Lavis and his team use modern organic chemistry to design and synthesize bright fluorescent labels for imaging structures inside livin

Autonomous Microscopy with Kevin Dean

Jul 08 2023 54 mins  
Kevin Dean is a professor at UT Southwestern pioneering autonomous microscopes and applying them to study rare biological events, mainly metastatic colonization. In our conversation we talk about his research and the current status of microscopy. Kevin was raised in a small town in Northern California earning his BA in Chemistry at Willamette University in Oregon, and was recognize