The Evidence Based Rheumatology Podcast

Apr 02 2025 100 ep. 15 mins 744
The Evidence Based Rheumatology Podcast artwork

A podcast for physicians about evidence based medicine in rheumatology. Each week we'll critique and apply a paper in the medical literature.

  Health & Fitness  Science
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E121: Obinutuzumab in SLE-LN

Apr 02 2025 18 mins  
Another day, another b cell podcast. Seems to be all the rage! This week I discuss the recently published NEJM trial of the anti CD20 agent obinutuzumab in lupus nephritis. Worth a read and listen, paper can be found here: https://www.nejm.org/doi/full/10.1056/NEJMoa2410965

E120: Real Life Use of PEXIVAS-Low

Mar 06 2025 24 mins  
What do you do when observational data and RCTs conflict? This week I'm covering the "real world PEXIVAS" study that was done by the French Vasculitis Study Group. Great read, interesting issues, have a listen and be sure to share with friends!

E119: Teclistamab for Rheumatology Writ Large

Feb 10 2025 10 mins  
One of my rare case-report podcasts, a topic that I typically avoid. The craze about CAR-T has also made me a little crazy, though, so I wanted to share what I think may be the ultimate destination for "more B cell depletion than rituximab" strategies. Article: https://www.nejm.org/doi/full/10.1056/NEJMc2407150

E118: The emerging risk of overdiagnosis in RA and PMR

Jan 31 2025 16 mins  
Podcast this week about overdiagnosis! Currently one of my favorite topics and something that I think will be an emerging issue in our field. We recently published a Viewpoint in Lancet Rheumatology (https://pubmed.ncbi.nlm.nih.gov/39341221/) addressing this issue. I'm going to read from it and after that will be giving a few final (spicy) thoughts on the topic. Hope you find it wo

E117: Inebilizumab for IgG4-RD (MITIGATE)

Dec 03 2024 12 mins  
New RCT in a new disease with a new drug! But is it as shiny as one would hope? Interesting discussion today about what a trial means, how it will affect practice, and how we could do better as a field. Happy holidays everyone!

E116: A New Paradigm for PMR

Nov 11 2024 9 mins  
Reading one of my recent newsletters this week, this one about PMR tapers. Be sure to subscribe at ebrheum.com if you want access to the visuals and upcoming editions!

E115: Benralizumab for EGPA - the MANDARA Study

Oct 28 2024 9 mins  
Quick rundown of an important rheumatology RCT this week, discussing the IL-5 inhibitor benralizumab for the treatment of relapsing/refractory EGPA. MANDARA Study: https://www.nejm.org/doi/full/10.1056/NEJMoa2311155

E114: Target Trials and STAR-RA with Rishi Desai

Oct 14 2024 31 mins  
Important methodology podcast this week, covering a lot of ground with expert epidemiologist Rishi Desai. Really enjoyed our conversation and glad to be publishing today! **House Keeping Note: we actually recorded this ~15 months ago but I somehow lost the audio... which somehow re-appeared! #technology STAR-RA: https://pubmed.ncbi.nlm.nih.gov/35027405/

E113: CAR-T is Coming to Rheumatology

Sep 30 2024 14 mins  
Exciting podcast this week about the upcoming / impending use of CAR-T in rheumatology. Highly recommend rheumatologists learn about this now; it's going to be a big thing for many years to come. In a future episode I will lay out my case for skepticism, but for now I think a good run down of the first big published series will be enough! NEJM CAR-T Case Series: https://www.nejm

E112: Gabapentin is Trash

Sep 12 2024 6 mins  
This week's podcast will be a quick read of one of my newsletters. The title basically speaks for itself! Find the newsletter and my other work at ebrheum.com